The biotransformation of soy isoflavones into ortho-hydroxyisoflavones by CYP105D7 from
Streptomyces avermitilis MA4680 is investigated through chimeric expression in Pichia …

Abstract Daidzin, daidzein 7-O-glucoside, is a major isoflavone in soybean and acts as a
phytoestrogen. By intestinal bacteria dietary, daidzin is hydrolyzed to the aglycone daidzein …

A β-glucosidase, efficiently hydrolyzing isoflavone glycoside to isoflavone aglycone, was
purified from Pichia guilliermondii K123-1, isolated from Korean soybean paste by …

8-Hydroxydaidzein (8-OHDe) is a non-natural isoflavone polyphenol isolated from
fermented soybean foods. 8-OHDe exhibits a wide range of pharmaceutical activities …

Abstract Daidzein C6 hydroxylase (6-DH, nfa12130), which is a class I type of cytochrome
P450 enzyme, catalyzes a hydroxylation reaction at the C6-position of the daidzein A-ring …

The use of soybean isoflavones in food products is limited due to their low hydrophilicity. To
enhance its solubility, the isoflavone daidzin was transglycosylated as a model compound …

Stereochemical course of isoflavanone dihydrodaidzein (DHD) reduction into the isoflavan
(3 S)-equol via tetrahydrodaidzein (THD) by the human intestinal anaerobic bacterium …

An Escherichia coli library comprising 8,424 strains incorporating gene fragments of the
equol-producing bacterium Slackia sp. strain NATTS was constructed and screened for E …

Biochanin A and formononetin are methylated isoflavones, abundant in legumes, which can
be converted in genistein and daidzein by means of an O-demethylation reaction. Our …

CYP57B3 from Aspergillus oryzae was recently discovered to catalyze the ortho-
hydroxylation of the soyisoflavone genistein. In the present study, the gene encoding …