Phosphate binding therapy to lower serum fibroblast-growth-factor-23 concentrations in chronic kidney disease: rationale and study design of the Sevelamer on …

AY Adema, MA de Jong, MH de Borst, PM Ter Wee… - Nephron, 2016 - karger.com
Background: Increased levels of phosphate and fibroblast growth factor-23 (FGF23) are
strong predictors of cardiovascular morbidity and mortality in patients with chronic kidney …

Effect of a non-calcium-based phosphate binder on fibroblast growth factor 23 in chronic kidney disease

C Spatz, K Roe, E Lehman, N Verma - Nephron Clinical Practice, 2013 - karger.com
Background: Elevated fibroblast growth factor 23 (FGF23) levels are associated with
progression of chronic kidney disease (CKD) and increased mortality. Studies in individuals …

[HTML][HTML] Effect of different phosphate binders on fibroblast growth factor 23 levels in patients with chronic kidney disease: a systematic review and meta-analysis of …

SJ Zhao, ZX Wang, L Chen, FX Wang… - Annals of Palliative …, 2022 - apm.amegroups.org
Background: Serum intact fibroblast growth factor 23 (FGF23) levels are progressively
increased in relation to the severity of kidney dysfunction. High serum intact FGF23 …

The effects of tenapanor on serum fibroblast growth factor 23 in patients receiving hemodialysis with hyperphosphatemia

GA Block, DP Rosenbaum, A Yan… - Nephrology Dialysis …, 2019 - academic.oup.com
Background Elevated serum fibroblast growth factor 23 (FGF23) is strongly associated with
cardiovascular risk and mortality. Tenapanor, an inhibitor of gastrointestinal …

Effects of lower versus higher phosphate diets on fibroblast growth factor-23 levels in patients with chronic kidney disease: a systematic review and meta-analysis

WC Tsai, HY Wu, YS Peng, SP Hsu… - Nephrology Dialysis …, 2018 - academic.oup.com
Background Elevated fibroblast growth factor-23 (FGF23) levels increase the risk of
cardiovascular diseases in patients with chronic kidney disease (CKD). We aimed to …

[HTML][HTML] Impact of fractional phosphate excretion on the relation of FGF23 with outcome in CKD patients

AP Bech, A Bouma-de Krijger, AD van Zuilen… - Journal of …, 2015 - Springer
Background Cardiovascular risk is increased in patients with chronic kidney disease (CKD).
Fibroblast growth factor 23 (FGF23) has emerged as an important, independent predictor of …

[HTML][HTML] Update on fibroblast growth factor 23 in chronic kidney disease

M Wolf - Kidney international, 2012 - Elsevier
Chronic kidney disease (CKD) is a public health epidemic that affects millions of people
worldwide. Presence of CKD predisposes individuals to high risks of end-stage renal …

[HTML][HTML] Changes in fibroblast growth factor 23 levels in normophosphatemic patients with chronic kidney disease stage 3 treated with lanthanum carbonate: results of …

P Ureña-Torres, D Prié, K Keddad, P Preston, P Wilde… - BMC nephrology, 2014 - Springer
Background High levels of circulating fibroblast growth factor 23 (FGF23) are associated
with chronic kidney disease (CKD) progression and high mortality. In the Phosphate …

[HTML][HTML] Phosphate control in reducing FGF23 levels in hemodialysis patients

C Rodelo-Haad, ME Rodríguez-Ortiz, A Martin-Malo… - PLoS …, 2018 - journals.plos.org
Background In hemodialysis patients, high levels of Fibroblast Growth Factor 23 (FGF23)
predict mortality. Our study was designed to test whether the control of serum phosphate is …

Roles of phosphate and fibroblast growth factor 23 in cardiovascular disease

JJ Scialla, M Wolf - Nature Reviews Nephrology, 2014 - nature.com
Disturbances in phosphate homeostasis are common in patients with chronic kidney
disease. As kidney function declines, circulating concentrations of phosphate and the …