Assessment of αvβ3 integrin expression after myocardial infarction by positron emission tomography

T Higuchi, FM Bengel, S Seidl… - Cardiovascular …, 2008 - academic.oup.com
Aims The purpose of this study was to determine the feasibility of a new positron emission
tomography (PET) imaging approach using an 18F-labelled αvβ3 integrin antagonist (18F …

Molecular imaging of early αvβ3 integrin expression predicts long-term left-ventricle remodeling after myocardial infarction in rats

HM Sherif, A Saraste, SG Nekolla, E Weidl… - Journal of Nuclear …, 2012 - Soc Nuclear Med
18F-galacto-RGD (18F-RGD) is a PET tracer binding to αvβ3 integrin receptors that are
upregulated after myocardial infarction (MI) as part of the healing process. We studied …

Imaging of αvβ3 integrin expression in experimental myocardial ischemia with [68Ga]NODAGA-RGD positron emission tomography

M Grönman, M Tarkia, T Kiviniemi, P Halonen… - Journal of Translational …, 2017 - Springer
Background Radiolabeled RGD peptides detect α v β 3 integrin expression associated with
angiogenesis and extracellular matrix remodeling after myocardial infarction. We studied …

PET imaging of angiogenesis after myocardial infarction/reperfusion using a one-step labeled integrin-targeted tracer 18F-AlF-NOTA-PRGD2

H Gao, L Lang, N Guo, F Cao, Q Quan, S Hu… - European journal of …, 2012 - Springer
Purpose The α v β 3 integrin represents a potential target for noninvasive imaging of
angiogenesis. The purpose of this study was to evaluate a novel one-step labeled integrin α …

In vivo molecular imaging of angiogenesis, targeting αvβ3 integrin expression, in a patient after acute myocardial infarction

MR Makowski, U Ebersberger, S Nekolla… - European heart …, 2008 - academic.oup.com
A 35-year-old Caucasian male presented with chest pain and nausea in the emergency
room. The initial ECG displayed sinus-rhythm with ST elevation in I, aVL, V1–5, ST …

Multiparametric PET and MRI of myocardial damage after myocardial infarction: correlation of integrin αvβ3 expression and myocardial blood flow

MR Makowski, C Rischpler, U Ebersberger… - European Journal of …, 2021 - Springer
Purpose Increased angiogenesis after myocardial infarction is considered an important
favorable prognostic parameter. The αvβ3 integrin is a key mediator of cell-cell and cell …

Feasibility of [18F]-RGD for ex vivo imaging of atherosclerosis in detection of αvβ3 integrin expression

R Golestani, L Mirfeizi, CJ Zeebregts, J Westra… - Journal of Nuclear …, 2015 - Elsevier
Background Inflammation and angiogenesis play an important role in atherosclerotic plaque
rupture. Therefore, molecular imaging of these processes could be used for determination of …

Dimeric [68Ga]DOTA-RGD Peptide Targeting αvβ3 Integrin Reveals Extracellular Matrix Alterations after Myocardial Infarction

M Kiugel, I Dijkgraaf, V Kytö, S Helin… - Molecular imaging and …, 2014 - Springer
Purpose We evaluated a dimeric RGD-peptide,[68 Ga] DOTA-E-[c (RGDfK)] 2, for positron
emission tomography (PET) imaging of myocardial integrin expression associated with …

Comparison of cyclic RGD peptides for αvβ3 integrin detection in a rat model of myocardial infarction

I Laitinen, J Notni, K Pohle, M Rudelius, E Farrell… - EJNMMI research, 2013 - Springer
Background Expression of α v β 3 integrin is increased after myocardial infarction as part of
the repair process. Increased expression of α v β 3 has been shown by molecular imaging …

MicroPET/CT imaging of αvβ3 integrin via a novel 68Ga-NOTA-RGD peptidomimetic conjugate in rat myocardial infarction

L Menichetti, C Kusmic, D Panetta, D Arosio… - European journal of …, 2013 - Springer
Purpose The α v β 3 integrin is expressed in angiogenic vessels and is a potential target for
molecular imaging of evolving pathological processes. Its expression is upregulated in …