Siglecs (Sialic acid-binding immunoglobulin-type lectins) are a I-type lectin that typically
binds sialic acid. Siglecs are predominantly expressed in immune cells and generate …

Sialic acid-binding Ig superfamily lectins (Siglecs) are members of the Ig superfamily that
recognize sialic acid residues of glycoproteins. Siglec-11 is a recently identified human …

Sialic acid binding immunoglobulin-like lectins (Siglecs) are cell surface receptors of
microglia and oligodendrocytes that recognize the sialic acid cap of healthy neurons and …

Sialic acid immunoglobulin-like lectin E (Siglec-E) is a subtype of pattern recognition
receptors found on the surface of myeloid cells and functions as a key immunosuppressive …

Background: Sialic acid binding immunoglobulin-like lectins (Siglecs) are cell surface
receptors that recognize sialic acids and may attenuate immune responses and reduce …

Sialic acid-binding Ig-like lectins (Siglecs) are members of the Ig superfamily that recognize
sialic acid residues of glycoproteins. Siglec-E is a mouse CD33-related Siglec that …

Microglia are resident myeloid cells in the central nervous system (CNS) with a unique
developmental origin, playing essential roles in developing and maintaining the CNS …

Siglecs are sialic-acid-binding immunoglobulin-like lectins involved in cell–cell interactions
and signalling functions in the haemopoietic, immune and nervous systems. Significant …

Most sialic acid–binding immunoglobulin-like lectins (Siglecs) suppress immune cell
function but are expressed at low levels on human T cells. We found that soluble CD52 …

Microglia are the innate sentinels of the central nervous system (CNS) and are responsible
for the homeostasis and immune defense of the CNS. Under the influence of the local …