OBJECTIVES.: Carboplatin dosing is usually based on glomerular filtration rate (GFR). The
Cockcroft–Gault and the Modified Diet in Renal Disease (MDRD) Study formulae are based …

Background: Cytotoxic agents have a narrow therapeutic window. A high percentage of
some of them is renally excreted in unchanged form. Accurate assessment of an individual's …

Abstract Purpose Creatinine clearance (Ccr) is used as a marker of renal function in cancer
chemotherapy, but it is not correlated with glomerular filtration rate (GFR) after high-dose …

Assessment of kidney function in oncology patients is a fundamental factor in profiling the
survival risk, determining the appropriate dose of chemotherapeutic drugs, and defining a …

In patients with cancer treated with cisplatin, carboplatin or methotrexate creatinine
clearance calculated using the Cockcroft‐Gault formula was compared with measured …

The creatinine clearance was calculated in standard fashion from a timed urine specimen
(measured creatinine clearance [MCC]) and from a previously published formula (estimated …

To compare glomerular filtration rate measured by technetium-99m ([Tc 99m]) DTPA
clearance with estimated creatinine clearance (CrCl)(Cockcroft and Gault (C&G) method) in …

Estimates of glomerular filtration rate (eGFR) are widely used when administering
nephrotoxic chemotherapy. No studies performed in oncology patients have shown whether …

Background: The glomerular filtration rate (GFR) is essential for calculating the dose and the
monitoring of carboplatin. Although GFR measurement (mGFR) by external markers is ideal …

Background Kidney function assessment by estimated glomerular filtration rate (eGFR)
equations, such as the Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) …