Aims Ibuprofen arginate is a highly soluble salt formed by combining racemic ibuprofen with
the amino acid l-arginine. This formulation is absorbed faster, and it is safe and effective in …

Background The traditional analgesics used to treat neuropathic pain such as
anticonvulsants, opioids, and nonsteroidal anti-inflammatory drugs (NSAIDs) lack efficacy …

Ibuprofen is one of the most frequently used analgesics. One of the concerns related with the
oral administration of conventional ibuprofen is the relatively slow absorption, which is …

Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit fatty acid amidohydrolase (FAAH), the
enzyme responsible for the metabolism of anandamide, an endocannabinoid. The analgesic …

Pain is a complex phenomenon that is influenced by physical, psychological, emotional and
social factors. Nonsteroidal anti-inflammatory drugs (NSAIDs) play a fundamental role in the …

The effects of methyleugenol, an essential oil isolated from Asiasari radix, on antinociception
were examined using the formalin test in mice. Oral administration of 10 mg/kg …

The main aim of the study was to examine analgesic effects of the topical opioids and non-
steroidal anti-inflammatory drugs (NSAIDs) in a radiant heat tail-flick nociception model …

Currently, several ibuprofen compounds are available on the market, differing in terms of
pharmaceutical composition that influence the pharmacokinetic profile and eventually the …

Ibuprofen is a safe and effective analgesic, but some formulations have a slow onset of
action. Ibuprofen arginate is a rapidly absorbed salt designed to promote more rapid onset …

Objective: The interactions of α-adrenoceptors with the antinociceptive effects of non-
steroidal anti-inflammatory drugs (NSAIDs) were assessed in acute thermal nociception in …