Roles of E6 and E7 human papillomavirus proteins in molecular pathogenesis of cervical cancer

E Taghizadeh, S Jahangiri, D Rostami… - Current Protein and …, 2019 - ingentaconnect.com
Human papillomavirus (HPV) cancers are expected to be major global health concerns in
the upcoming decades. The growth of HPV-positive cancer cells depends on the consistent …

Human papillomavirus type 16 E5 oncoprotein as a new target for cervical cancer treatment

MK Kim, HS Kim, SH Kim, JM Oh, JY Han… - Biochemical …, 2010 - Elsevier
Human papillomavirus (HPV) infection is considered to be the necessary cause of cervical
cancer. E6 and E7 oncoproteins of HPV have been known to play major roles in malignant …

E6 and E7 oncoproteins: Potential targets of cervical cancer

RR Malla, MA Kamal - Current Medicinal Chemistry, 2021 - ingentaconnect.com
Cervical cancer (CC) is the fourth leading cancer in women in the age group of 15-44 years
globally. Experimental as well as epidemiological studies identified that type16 and 18 HPV …

[HTML][HTML] Human papillomavirus E6 and E7: the cervical cancer hallmarks and targets for therapy

A Pal, R Kundu - Frontiers in microbiology, 2020 - frontiersin.org
Human papillomavirus (HPV)-induced cervical cancer is a major health issue among
women from the poorly/under-developed sectors of the world. It accounts for a high-mortality …

Human papillomavirus-16 E5 protein: oncogenic role and therapeutic value

N Ganguly - Cellular oncology, 2012 - Springer
Background Human papillomavirus (HPV) is a non-enveloped, double-stranded DNA virus.
HPV infection occurs through sexual route, and the virus infects mucosal and cutaneous …

Cellular functions of HPV16 E5 oncoprotein during oncogenic transformation

L Gutierrez-Xicotencatl, A Pedroza-Saavedra… - Molecular Cancer …, 2021 - AACR
The human papillomavirus (HPV) is recognized as the main etiologic agent associated with
cervical cancer. HPVs are epitheliotropic, and the ones that infect the mucous membranes …

[PDF][PDF] Role of HR-HPVs E6 and E7 oncoproteins in cervical carcinogenesis

P Gariglio, J Organista-Nava, E Alvarez-Rios - J Mol Genet Med, 2016 - researchgate.net
Abstract The strategies that High Risk Human Papillomavirus (HR-HPVs) have developed in
differentiating epithelial cells to reach a DNA-synthesis competent state are basically related …

[HTML][HTML] Functional roles of E6 and E7 oncoproteins in HPV-induced malignancies at diverse anatomical sites

V Tomaić - Cancers, 2016 - mdpi.com
Approximately 200 human papillomaviruses (HPVs) infect human epithelial cells, of which
the alpha and beta types have been the most extensively studied. Alpha HPV types mainly …

New HPV E6 binding proteins: dangerous liaisons?

MHG Kubbutat, KH Vousden - Trends in Microbiology, 1998 - cell.com
(HPVs) are by far the best characterized of the human tumor viruses and, as they contribute
to the development of almost all cervical cancers, represent a major disease worldwide. The …

Immunohistochemical evaluation of E6/E7 HPV oncoproteins staining in cervical cancer

A Stiasny, C Kuhn, D Mayr, C Alexiou… - Anticancer …, 2016 - ar.iiarjournals.org
Background/Aim: High-risk human papillomavirus (HPV) subtypes (ie 16 and 18) lead to
uterine cervical cancer as well as HPV-positive oropharyngeal cancer (OSCC), a form of …