Photoperiod at conception predicts C677T‐MTHFR genotype: A novel gene‐environment interaction
M Lucock, T Glanville, L Ovadia, Z Yates… - American Journal of …, 2010 - Wiley Online Library
Data is presented, which suggest that the day length a woman experiences during the
periconceptional period predicts the C677T‐MTHFR genotype of her child. Logistic …
periconceptional period predicts the C677T‐MTHFR genotype of her child. Logistic …
Adaptive developmental plasticity in methylene tetrahydrofolate reductase (MTHFR) C677T polymorphism limits its frequency in South Indians
SM Naushad, C Krishnaprasad, ARR Devi - Molecular biology reports, 2014 - Springer
Methylene tetrahydrofolate reductase (MTHFR) C677T polymorphism shows considerable
heterogeneity in its distribution in humans worldwide. The current study was conducted to …
heterogeneity in its distribution in humans worldwide. The current study was conducted to …
Folate-mediated one-carbon metabolism and its effect on female fertility and pregnancy viability
M Laanpere, S Altmäe, A Stavreus-Evers… - Nutrition …, 2010 - academic.oup.com
This review summarizes current knowledge of the effect of folate-mediated one-carbon
metabolism and related genetic variants on female fertility and pregnancy viability …
metabolism and related genetic variants on female fertility and pregnancy viability …
Fetal folate C677T methylenetetrahydrofolate reductase gene polymorphism and low birth weight
T Glanville, Z Yates, L Ovadia, JJ Walker… - Journal of obstetrics …, 2006 - Taylor & Francis
The aim of this study was to determine if fetal C677T methylenetetrahydrofolate reductase
(MTHFR) genotype contributes to low birth weight. The study group consisted of 243 term …
(MTHFR) genotype contributes to low birth weight. The study group consisted of 243 term …
High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory …
RH Bahous, NM Jadavji, L Deng… - Human molecular …, 2017 - academic.oup.com
Methylenetetrahydrofolate reductase (MTHFR) generates methyltetrahydrofolate for
methylation reactions. Severe MTHFR deficiency results in homocystinuria and neurologic …
methylation reactions. Severe MTHFR deficiency results in homocystinuria and neurologic …
A paternal effect of MTHFR SNPs on gametes and embryos should not be overlooked
L Jacquesson-Fournols, S Alvarez, M Cohen… - Journal of Assisted …, 2019 - Springer
The process of methylation is a major biochemical component of all cells, essential in
allowing covalent linking of methyl groups to lipids, proteins, and nucleic acids. It is involved …
allowing covalent linking of methyl groups to lipids, proteins, and nucleic acids. It is involved …
MTHFR 677TT genotype and disease risk: is there a modulating role for B-vitamins?
Methylenetetrahydrofolate reductase (MTHFR) is a critical folate-metabolising enzyme which
requires riboflavin as its co-factor. A common polymorphism (677C→ T) in the MTHFR gene …
requires riboflavin as its co-factor. A common polymorphism (677C→ T) in the MTHFR gene …
Polymorphisms in the MTHFR gene influence embryo viability and the incidence of aneuploidy
M Enciso, J Sarasa, L Xanthopoulou, S Bristow… - Human genetics, 2016 - Springer
MTHFR is an important enzyme in the metabolism of folic acid and is crucial for reproductive
function. Variation in the sequence of MTHFR has been implicated in subfertility, but …
function. Variation in the sequence of MTHFR has been implicated in subfertility, but …
Solar cycle predicts folate-sensitive neonatal genotypes at discrete phases of the first trimester of pregnancy: a novel folate-related human embryo loss hypothesis
Folate, a key periconceptional nutrient, is ultraviolet light (UV-R) sensitive. We therefore
hypothesise that a relationship exists between sunspot activity, a proxy for total solar …
hypothesise that a relationship exists between sunspot activity, a proxy for total solar …
Embryonic MTHFR contributes to blastocyst development
H Ishitani, S Ikeda, K Egashira, M Sugimoto… - Journal of Assisted …, 2020 - Springer
Purpose Reduction in methylenetetrahydrofolate reductase (MTHFR) activity due to genetic
variations in the MTHFR gene has been controversially implicated in subfertility in human in …
variations in the MTHFR gene has been controversially implicated in subfertility in human in …