For many years, central dogma defined multiple sclerosis (MS) as a T cell-driven
autoimmune disorder; however, over the past decade there has been a burgeoning …

The cause and the pathogenic mechanisms leading to multiple sclerosis (MS), a chronic
inflammatory disease of the central nervous system (CNS), are still under scrutiny. During …

B lymphocytes have essential roles in the autoimmune pathogenesis of multiple sclerosis
(MS). They regulate the autoimmune response and participate in the development of the …

Historically, multiple sclerosis (MS) has been viewed as being primarily driven by T cells.
However, the effective use of anti-CD20 treatment now also reveals an important role for B …

Over the last decade, evidence condensed that B cells, B cell-derived plasma cells and
antibodies play a key role in the pathogenesis and progression of multiple sclerosis (MS). In …

Multiple sclerosis (MS) is a neurodegenerative disease of the central nervous system (CNS),
traditionally considered a chronic autoimmune attack against the insulating myelin sheaths …

While it was long held that T cells were the primary mediators of multiple sclerosis (MS)
pathogenesis, the beneficial effects observed in response to treatment with Rituximab (RTX) …

Antibody‐secreting cells (ASCs) play a fundamental role in humoral immunity. The aberrant
function of ASCs is related to a number of disease states, including autoimmune diseases …

Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system
with no clear etiology. Until recently, most studies have emphasized the role of T cells in the …

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system. Although most studies have emphasized the role of T cells in the pathogenesis of …