B cells are one of the key players in the pathogenesis of multiple sclerosis (MS). The
peripheral B cell distributions are similar in healthy persons and MS patients. In healthy …

In 1957, Holborow and colleagues 1 identified antibodies targeting cell nuclei in lupus sera,
thereby linking B cells to the pathogenesis of human systemic lupus erythematosus (SLE). In …

MS is an autoimmune disease, in which T and B cells play a crucial role. B cells can be
involved in MS by different mechanisms such as presentation of antigens to T cells, transport …

B cells and antibodies account for the most prominent immunodiagnostic feature in patients
with multiple sclerosis (MS), namely oligoclonal bands. Furthermore, evidence is …

Background B cell depletion therapy is highly effective in relapsing-remitting multiple
sclerosis (RRMS). However, the precise underlying mechanisms of action for its biological …

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS)
known for the manifestation of demyelinated lesions throughout the CNS, leading to …

The most common laboratory abnormality in multiple sclerosis (MS) is an increased amount
of cerebrospinal fluid IgG and the presence of oligoclonal bands. Despite studies of the …

Autoimmune diseases are characterized by the recognition of self‐antigens by the immune
system, which leads to inflammation and tissue damage. B cells are directly and indirectly …

Epstein–Barr virus (EBV) infection of B cells is associated with increased multiple sclerosis
(MS) susceptibility. Recently, we found that CXCR3‐expressing B cells preferentially …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS). The mainstream view is that MS is caused by an autoimmune attack …