Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central
nervous system (CNS) that traditionally has been considered to be mediated primarily by T …

B cells are essential components of the adaptive immune system and have important roles
in the pathogenesis of several central nervous system (CNS) diseases. Besides producing …

The role of B cells in the pathogenesis of Multiple Sclerosis (MS), an autoimmune
neurodegenerative disease, is becoming eminent in recent years, but the specific …

Multiple sclerosis (MS) is a neurologic disease affecting myelinated nerves in the central
nervous system (CNS). The disease often debuts as a clinically isolated syndrome, eg, optic …

Epidemiological studies have demonstrated that Epstein-Barr virus (EBV) is a known
etiologic risk factor, and perhaps prerequisite, for the development of MS. EBV establishes …

Autoimmunity results from abnormal B‐and T‐cell recognition of self‐antigens, which leads
to autoantibody production in many cases. Autoantibodies produced by B‐cell‐derived …

Multiple sclerosis (MS) is a chronically progressive auto-immune mediated inflammatory
demyelinating disease of the central nervous system (CNS) which manifests as disturbances …

Epstein-Barr virus (EBV) is the infectious agent that shows the strongest association with
multiple sclerosis (MS). EBV is a ubiquitous double stranded DNA herpes virus that …

Growing evidences put B lymphocytes on a central stage in multiple sclerosis (MS)
immunopathology. While investigating the effects of interferon‐β (IFN‐β) therapy, one of the …

A hallmark of systemic lupus erythematosus (SLE) is aberrant B-cell differentiation and
function, and the pathogenic roles of B cells are multifaceted. In addition to producing …