Bioprinting-based PDLSC-ECM screening for in vivo repair of alveolar bone defect using cell-laden, injectable and photocrosslinkable hydrogels

Y Ma, Y Ji, T Zhong, W Wan, Q Yang, A Li… - ACS biomaterials …, 2017 - ACS Publications
Periodontitis is an inflammatory disease worldwide that may result in periodontal defect
(especially alveolar bone defect) and even tooth loss. Stem-cell-based approach combined …

Investigating the repair of alveolar bone defects by gelatin methacrylate hydrogels-encapsulated human periodontal ligament stem cells

J Pan, J Deng, L Yu, Y Wang, W Zhang, X Han… - Journal of Materials …, 2020 - Springer
Although various efforts have been made to develop effective treatments for alveolar bone
defect, alveolar regeneration has been emerging as the one with the most potential Herein …

Bioprinting 3D cell-laden hydrogel microarray for screening human periodontal ligament stem cell response to extracellular matrix

Y Ma, Y Ji, G Huang, K Ling, X Zhang, F Xu - Biofabrication, 2015 - iopscience.iop.org
Periodontitis is an inflammatory disease negatively affecting up to 15% of adults worldwide.
Periodontal ligament stem cells (PDLSCs) hold great promises for periodontal tissue …

Potential of an aligned porous hydrogel scaffold combined with periodontal ligament stem cells or gingival mesenchymal stem cells to promote tissue regeneration in …

W Wang, A Wang, G Hu, M Bian, L Chen… - ACS Biomaterials …, 2023 - ACS Publications
Periodontal tissue regeneration is a major challenge in tissue engineering due to its
regenerated environment complexity. It aims to regenerate not only the supporting alveolar …

Fabrication of gelatin methacrylate/nanohydroxyapatite microgel arrays for periodontal tissue regeneration

X Chen, S Bai, B Li, H Liu, G Wu, S Liu… - International journal of …, 2016 - Taylor & Francis
Introduction Periodontitis is a chronic infectious disease and is the major cause of tooth loss
and other oral health issues around the world. Periodontal tissue regeneration has therefore …

Bone repair using periodontal ligament progenitor cell-seeded constructs

G Tour, M Wendel, G Moll… - Journal of Dental …, 2012 - journals.sagepub.com
The success of tissue-engineering therapies is dependent on the ability of scaffolds to guide
differentiation of progenitor cells. Here we present a new approach using a biomimetic …

Periodontal ligament stem cell-based bioactive constructs for bone tissue engineering

Z Zhao, J Liu, MD Weir, A Schneider, T Ma… - … in Bioengineering and …, 2022 - frontiersin.org
Objectives: Stem cell-based tissue engineering approaches are promising for bone repair
and regeneration. Periodontal ligament stem cells (PDLSCs) are a promising cell source for …

3D bioprinting of a bioactive composite scaffold for cell delivery in periodontal tissue regeneration

G Miao, L Liang, W Li, C Ma, Y Pan, H Zhao, Q Zhang… - Biomolecules, 2023 - mdpi.com
Hydrogels have been widely applied to the fabrication of tissue engineering scaffolds via
three-dimensional (3D) bioprinting because of their extracellular matrix-like properties …

Alginate/hyaluronic acid hydrogel delivery system characteristics regulate the differentiation of periodontal ligament stem cells toward chondrogenic lineage

S Ansari, IM Diniz, C Chen, T Aghaloo, BM Wu… - Journal of Materials …, 2017 - Springer
Cartilage tissue regeneration often presents a challenging clinical situation. Recently, it has
been shown that Periodontal Ligament Stem Cells (PDLSCs) possess high chondrogenic …

A 3D‐bioprinted functional module based on decellularized extracellular matrix bioink for periodontal regeneration

X Yang, Y Ma, X Wang, S Yuan, F Huo, G Yi… - Advanced …, 2023 - Wiley Online Library
Poor fiber orientation and mismatched bone–ligament interface fusion have plagued the
regeneration of periodontal defects by cell‐based scaffolds. A 3D bioprinted biomimetic …