This study was conducted to examine whether oligonol, a low-molecular-weight polyphenol
derived from lychee fruit, has an ameliorative effect on diabetes-induced alterations, such as …

Plasma xanthine oxidoreductase (XOR) activity is high in metabolic disorders such as
diabetic mellitus, obesity, or overweight. Thus, this study investigated whether the XOR …

Background Diabetic nephropathy (DN) is one of the major causes of end-stage renal
disease in diabetic patients. Increasing evidence from studies in the rodents has suggested …

Aging kidneys are characterized by an increased vulnerability to glomerulosclerosis and a
measurable decline in renal function. Evidence suggests that renal and systemic klotho and …

Background Prolyl hydroxylase domain (PHD) inhibitors, which stimulate erythropoietin
production through the activation of hypoxia-inducible factor (HIF), are novel therapeutic …

Atypical antipsychotics, such as olanzapine, are commonly prescribed to patients with
schizophrenic symptoms and other psychiatric disorders. However, weight gain and …

The number of obese people in the world is growing rapidly worldwide and has reached
epidemic status. Obesity is often associated with the clustering of metabolic and …

Acute kidney injury (AKI) is a life-threatening complication that accompanies
rhabdomyolysis. Daidzein is a dietary isoflavone that has various biological activities. This …

Renal ischemia/reperfusion (I/R) is a common cause of acute kidney injury and remote liver
damage is an ultimate negative outcome. Current treatments for renal I/R typically involve …

Methods: Thirty male C57BL/6J mice (4-week-old) were randomly divided into 3 groups and
were fed normal diet, high-fat diet (HFD, 20% fat) and HFD+ 0.05%(w/w) eriodictyol for 16 …