Recent evidence suggests that troxerutin, a trihydroxyethylated derivative of natural
bioflavonoid rutin, exhibits beneficial effects on diabetes-related symptoms. Here we …

Obesity is a major risk factor for the development of type 2 diabetes, and both conditions are
now recognized to possess significant inflammatory components underlying their …

Recent findings suggest that neurotoxicity is the mechanism underlying the induction of
neuronal insulin resistance by a high cholesterol diet. Troxerutin, a naturally occurring …

Podocyte injury, a major contributor to the pathogenesis of diabetic nephropathy, is caused
at least in part by the excessive generation of reactive oxygen species (ROS) …

OBJECTIVE Despite the beneficial effects of resveratrol (RSV) on cardiovascular disease
and life span, its effects on type 2 diabetic nephropathy remain unknown. This study …

The present study was designed to investigate the antidiabetic effect of nerolidol on high-fat
diet and streptozotocin-induced diabetic rats. Type 2 diabetes was induced in animals by …

Background Osthole is a natural active ingredient extracted from the traditional Chinese
medicine Cnidium monnieri. It has been demonstrated to have anti-inflammatory, anti …

Introduction Obesity is a chronic metabolic disorder that results in excessive energy
accumulated in adipose tissue causing dysfunction of adipocytes, inflammation, and …

Background and Purpose Systemic oxidative stress associated with dietary calorie overload
plays an important role in the deterioration of vascular function in middle‐aged patients …

Aims/hypothesis Many of the effects of resveratrol are consistent with the activation of AMP-
activated protein kinase (AMPK), silent information regulator T1 (SIRT1) and peroxisome …