Myoglobin-deficient mice are viable and have preserved cardiac function due to their ability
to mount a complex compensatory response involving increased vascularization and the …

The physiological role of myoglobin (Mb) within the heart depends on its oxygenation state.
The myocardium exhibits a broad oxygen partial pressure (pO 2) spectrum with a transmural …

For more than 100 years, myoglobin has been among the most extensively studied proteins.
Since the first comprehensive review on myoglobin function as a dioxygen store by Millikan …

The mechanisms underlying subcellular oxygen transport mediated by myoglobin (Mb)
remain unclear. Recent evidence suggests that, in the myocardium, transverse diffusion of …

Myoglobin (Mb), besides its roles as an oxygen (O2) carrier/storage protein and nitric oxide
NO scavenger/producer, may participate in lipid trafficking and metabolite binding. Our …

In the context of the increasing number of obese individuals, a major problem is represented
by obesity and malnutrition in children. This condition is mainly ascribable to unbalanced …

Background The effects of diet-induced obesity on skeletal muscle function are largely
unknown, particularly as it relates to changes in oxidative metabolism and morphology …

The regulation of euglycemia is essential for human health with both chronic hypoglycemia
and hyperglycemia having detrimental effects. It is well documented that the incidence of …

At onset of muscle contraction, myoglobin (Mb) immediately releases its bound O2 to the
mitochondria. Accordingly, intracellular O2 tension (PmbO2) markedly declines in order to …

Myoglobin (MB) belongs to the well-studied globin proteins superfamily. It has been
extensively studied for its physiological roles in oxygen storage and transport for about a …