Corynebacterium glutamicum as a Host for Synthesis and Export of d-Amino Acids

N Stäbler, T Oikawa, M Bott, L Eggeling - Journal of bacteriology, 2011 - Am Soc Microbiol
ABSTRACT A number of d-amino acids occur in nature, and there is growing interest in their
function and metabolism, as well as in their production and use. Here we use the well …

Elucidation of anaplerotic pathways in Corynebacterium glutamicum via 13C-NMR spectroscopy and GC-MS

SM Park, C Shaw-Reid, AJ Sinskey… - Applied microbiology …, 1997 - Springer
We have obtained direct evidence indicating the presence of pyruvate-carboxylating activity
in Corynebacterium glutamicum, a lysine-overproducing bacterium. This evidence was …

[HTML][HTML] Effect of Tween 40 and DtsR1 on l-arginine overproduction in Corynebacterium crenatum

M Chen, X Chen, F Wan, B Zhang, J Chen… - Microbial Cell …, 2015 - Springer
Background l-Glutamate is an important precursor in the l-arginine (l-Arg) biosynthetic
pathway. Various methods, including polyoxyethylene sorbitan monopalmitate (Tween 40) …

Reengineering of a Corynebacterium glutamicuml-Arginine and l-Citrulline Producer

M Ikeda, S Mitsuhashi, K Tanaka… - Applied and …, 2009 - Am Soc Microbiol
Toward the creation of a robust and efficient producer of l-arginine and l-citrulline
(arginine/citrulline), we have performed reengineering of a Corynebacterium glutamicum …

Glutamine metabolism of Corynebacterium glutamicum: role of the glutaminase GlsK

J Buerger, N Rehm, L Grebenstein… - FEMS microbiology …, 2016 - academic.oup.com
Corynebacterium glutamicum is able to metabolize different nitrogen and carbon sources. In
standard minimal media, ammonium and urea typically serve as nitrogen source and …

Pathway analysis and metabolic engineering in Corynebacterium glutamicum

H Sahm, L Eggeling, AA Graaf - 2000 - degruyter.com
Abstract The Gram-positive bacterium Corynebacterium glutamicum is used for the industrial
production of amino acids, eg of L-glutamate and L-lysine. During the last 15 years, genetic …

Metabolic design in amino acid producing bacterium Corynebacterium glutamicum

H Sahm, L Eggeling, B Eikmanns… - FEMS Microbiology …, 1995 - academic.oup.com
Abstract The Gram-positive bacterium Corynebacterium glutamicum is used for the industrial
production of amino acids, eg of l-glutamate and l-lysine. In the last 10 years, genetic …

Metabolic engineering of Corynebacterium glutamicum for L-tyrosine production from glucose and xylose

B SARIYAR AKBULUT - 2023 - openaccess.marmara.edu.tr
Abstract© 2023 Elsevier BV Microbial production of aromatic compounds is an attractive and
sustainable biotechnological approach. With this motivation, here metabolic engineering of …

Export of amino acids and other solutes

L Eggeling - … of Corynebacterium glutamicum. CRC Press, Boca …, 2005 - books.google.com
After the discovery that Corynebacterium glutamicum can easily be influenced to excrete L-
glutamate, powerful producers were rapidly developed for this amino acid and for L-lysine …

Flux partitioning in the split pathway of lysine synthesis in Corynebacterium glutamicum Quantification by 13C‐ and 1H‐NMR spectroscopy

K Sonntag, L Eggeling, AA De Graaf… - European journal of …, 1993 - Wiley Online Library
The Gram‐positive Corynebacterium glutamicum has the potential to synthesize l‐lysine via
a split pathway, where amino‐ketopimelate is converted to the ultimate lysine precursor …