In-Depth Profiling of Lysine-Producing Corynebacterium glutamicum by Combined Analysis of the Transcriptome, Metabolome, and Fluxome

JO Kromer, O Sorgenfrei, K Klopprogge… - Journal of …, 2004 - Am Soc Microbiol
An in-depth analysis of the intracellular metabolite concentrations, metabolic fluxes, and
gene expression (metabolome, fluxome, and transcriptome, respectively) of lysine …

Fermentative production of lysine by Corynebacterium glutamicum: transmembrane transport and metabolic flux analysis

T Tryfona, MT Bustard - Process Biochemistry, 2005 - Elsevier
Since the 1950s the production of amino acids by fermentative methods has become a very
important aspect of industrial microbiology, leading to numerous studies to understand and …

[PDF][PDF] Untersuchungen zur in vivo Aktivität anaplerotischer Stoffwechselwege in Corynebacterium glutamicum mittels 13C-Markierungstechnik

S Petersen - 2001 - juser.fz-juelich.de
Corynebacterium glutamicum wird technisch zur Herstellung der Aminosäure L-Lysin
eingesetzt. Oxalacetat, das Vorläufermetabolit der Lysinsynthese ist, wird in C. glutamicum …

Metabolic engineering of Corynebacterium glutamicum for L-tyrosine production from glucose and xylose

E Kurpejović, A Burgardt, GM Bastem, N Junker… - Journal of …, 2023 - Elsevier
Microbial production of aromatic compounds is an attractive and sustainable
biotechnological approach. With this motivation, here metabolic engineering of …

Identification of a suppressor gene for the arginine-auxotrophic argJ mutation in Corynebacterium glutamicum

GH Hwang, JY Cho - Journal of Industrial Microbiology and …, 2010 - academic.oup.com
We recently proposed a metabolic engineering strategy for l-ornithine production based on
the hypothesis that an increased intracellular supply of N-acetylglutamate may further …

A Mutation in the Corynebacterium glutamicum ltsA Gene Causes Susceptibility to Lysozyme, Temperature-Sensitive Growth, and l-Glutamate Production

T Hirasawa, M Wachi, K Nagai - Journal of bacteriology, 2000 - Am Soc Microbiol
The Corynebacterium glutamicum mutant KY9714, originally isolated as a lysozyme-
sensitive mutant, does not grow at 37° C. Complementation tests and DNA sequencing …

Flux through the tetrahydrodipicolinate succinylase pathway is dispensable for l-lysine production in Corynebacterium glutamicum

CA Shaw-Reid, MM McCormick, AJ Sinskey… - Applied microbiology …, 1999 - Springer
The N-succinyl-ll-diaminopimelate desuccinylase gene (dapE) in the four-step succinylase
branch of the l-lysine biosynthetic pathway of Corynebacterium glutamicum was disrupted …

Expression of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase improve L-citrulline biosynthesis in argG-deleted Corynebacterium …

Z Liu, L Chen, N Hao, L Xu, Y Li, M Yan… - Advances in Applied …, 2015 - Springer
Corynebacterium glutamicum, a well-known producer in the amino acids industry, has
become a potential platform organism for synthetic biology in industrial biotechnology …

Identification and characterization of the last two unknown genes, dapC and dapF, in the succinylase branch of the L-lysine biosynthesis of Corynebacterium …

M Hartmann, A Tauch, L Eggeling, B Bathe… - Journal of …, 2003 - Elsevier
The inspection of the complete genome sequence of Corynebacterium glutamicum ATCC
13032 led to the identification of dapC and dapF, the last two unknown genes of the …

Biochemische, biotechnologische und molekularbiologische Analyse eines Signaltransduktionsweges in Corynebacterium glutamicum

M Silberbach - 2004 - kups.ub.uni-koeln.de
Das gram-positive Bodenbakterium Corynebacterium glutamicum hat seit seiner
Entdeckung in den 1950er Jahren eine herausragende industrielle Bedeutung erlangt. Auf …