Identification of transmembrane protein 237 as a novel interactor with the intestinal riboflavin transporter-3 (RFVT-3): role in functionality and cell biology

S Sabui, VS Subramanian, Q Pham… - American Journal of …, 2019 - journals.physiology.org
The apically localized riboflavin (RF) transporter-3 (RFVT-3) is involved in intestinal
absorption of vitamin B2. Previous studies have characterized different physiological …

Functional involvement of RFVT3/SLC52A3 in intestinal riboflavin absorption

H Yoshimatsu, A Yonezawa, Y Yao… - American Journal …, 2014 - journals.physiology.org
Riboflavin, also known as vitamin B2, is transported across the biological membrane into
various organs by transport systems. Riboflavin transporter RFVT3 is expressed in the small …

Structure/functional aspects of the human riboflavin transporter-3 (SLC52A3): role of the predicted glycosylation and substrate-interacting sites

VS Subramanian, S Sabui… - … of Physiology-Cell …, 2017 - journals.physiology.org
The human riboflavin (RF) transporter-3 (hRFVT-3; product of the SLC52A3 gene) plays an
essential role in the intestinal RF absorption process and is expressed exclusively at the …

Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells

VS Subramanian, L Rapp… - American Journal of …, 2011 - journals.physiology.org
The water-soluble vitamin B2 (riboflavin, RF) is an essential micronutrient for normal cell
function and survival. Recent studies have identified a role for the human riboflavin …

[HTML][HTML] Molecular mechanisms mediating the adaptive regulation of intestinal riboflavin uptake process

VS Subramanian, A Ghosal, R Kapadia… - PLoS …, 2015 - journals.plos.org
The intestinal absorption process of vitamin B2 (riboflavin, RF) is carrier-mediated, and all
three known human RF transporters, ie, hRFVT-1,-2, and-3 (products of the SLC52A1, 2 & 3 …

[HTML][HTML] Identification of residues/sequences in the human riboflavin transporter-2 that is important for function and cell biology

VS Subramanian, R Kapadia, A Ghosal, HM Said - Nutrition & metabolism, 2015 - Springer
Background Riboflavin (RF) is essential for normal cellular metabolic activities. Human cells
obtain RF from their surroundings via a carrier-mediated process that involves RF …

Conditional (intestinal-specific) knockout of the riboflavin transporter-3 (RFVT-3) impairs riboflavin absorption

VS Subramanian, N Lambrecht… - American Journal of …, 2016 - journals.physiology.org
Riboflavin (RF) is indispensable for normal cell metabolism, proliferation, and growth. The
RFVT-3 protein (product of the Slc52a3 gene) is expressed in the gut with the expression …

Effect of the proinflammatory cytokine TNF-α on intestinal riboflavin uptake: inhibition mediated via transcriptional mechanism (s)

KY Anandam, OA Alwan… - … of Physiology-Cell …, 2018 - journals.physiology.org
Riboflavin (RF), is essential for normal cellular metabolism/function. Intestinal RF absorption
occurs via a specific carrier-mediated process that involves the apical transporter RFVT-3 …

[HTML][HTML] Functional characteristics of the human ortholog of riboflavin transporter 2 and riboflavin-responsive expression of its rat ortholog in the small intestine indicate …

M Fujimura, S Yamamoto, T Murata, T Yasujima… - The Journal of …, 2010 - Elsevier
Riboflavin transporter (RFT) 2 has recently been identified as a transporter that may be,
mainly based on the functional characteristics of its rat ortholog (rRFT2), involved in the …

Sodium butyrate enhances intestinal riboflavin uptake via induction of expression of riboflavin transporter-3 (RFVT3)

VS Subramanian, S Sabui, CW Heskett… - Digestive diseases and …, 2019 - Springer
Background Uptake of riboflavin (RF) by intestinal epithelial cells occurs via a specific carrier-
mediated process that involves the apically localized RF transporter-3 (RFVT3). Previous …