Riboflavin (vitamin B-2) was first isolated from milk whey in the late 1870s as the water-
soluble, yellowish pigment called lactochrome. By the 1930s, lactochrome was structurally …

The human sodium-dependent multivitamin transporter (hSMVT) mediates sodium-
dependent uptake of biotin in renal and intestinal epithelia. To date, however, there is …

Retinol-binding protein (RBP) is the specific plasma carrier of retinol, encharged of the
vitamin transport from the liver to target cells. Ligand binding influences the RBP affinity for …

The intestinal mucosal-to-serosal transport of riboflavin was examined using rat everted
sacs. Maximum transport of 0.5 μM riboflavin occurred in the proximal small intestine …

The primary function of cobalamin (Cbl; vitamin B12) is the formation of red blood cells and
the maintenance of a healthy nervous system. Before cells can utilise dietary Cbl, the vitamin …

Vitamin A (retinol) is absorbed in the small intestine, stored in liver, and secreted into
circulation bound to serum retinol-binding protein (RBP4). Circulating retinol may be taken …

Background The human thiamine transporter-2 (hTHTR-2) is involved in the intestinal
absorption of thiamine. Recent studies with membrane transporters of other …

The major cellular pathway for uptake of the vitamin folic acid, including its absorption in the
intestine, is via a plasma membrane carrier system, the reduced folate carrier (RFC). Very …

STRA6 is a plasma membrane protein that mediates the transport of vitamin A, or retinol,
from plasma retinol binding protein (RBP) into the cell. Mutations in human STRA6 are …

The human sodium-dependent vitamin C transporter-2 (hSVCT2) plays an important role in
cellular accumulation of ascorbic acid in liver cells. However, little is known about the …