The effect of zofenopril on the cardiovascular system of spontaneously hypertensive rats treated with the ACE2 inhibitor MLN-4760

S Cacanyiova, M Cebova, F Simko, T Baka… - Biological Research, 2023 - Springer
Background Angiotensin converting enzyme 2 (ACE2) plays a crucial role in the infection
cycle of SARS-CoV-2 responsible for formation of COVID-19 pandemic. In the …

Vascular Effects of Low-Dose ACE2 Inhibitor MLN-4760—Benefit or Detriment in Essential Hypertension?

A Berenyiova, I Bernatova, A Zemancikova, M Drobna… - Biomedicines, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infects host cells through
angiotensin-converting enzyme 2 (ACE2). Concurrently, the product of ACE2 action …

Cardiovascular changes in spontaneously hypertensive rats are improved by chronic treatment with zofenopril

M Gómez‐Roso, MJ Montero, R Carrón… - British journal of …, 2009 - Wiley Online Library
Background and purpose: The aim of this study was to investigate the effect of chronic
treatment with antihypertensive and non‐antihypertensive doses of zofenopril on …

Effect of renin angiotensin blockers on angiotensin converting enzyme 2 level in cardiovascular patients

S Farid Fahmy, MO El Derany, H Khorshid… - BMC Pharmacology and …, 2023 - Springer
Background Renin–angiotensin–aldosterone system (RAAS) is hypothesized to be in the
center of COVID pathophysiology as the angiotensin converting enzyme 2 (ACE2) …

Sepiapterin decreases vasorelaxation in nitric oxide synthase inhibition–induced hypertension

BM Mitchell, AM Dorrance, A Ergul… - Journal of …, 2004 - journals.lww.com
Exogenous BH4 (tetrahydrobiopterin) has been shown to improve endothelial function in
cardiovascular disease; however, in the presence of elevated superoxide levels and …

Dysregulation of the renin-angiotensin-aldosterone system (RAA) in patients infected with SARS-CoV-2-possible clinical consequences

A Dettlaff-Pokora, J Swierczynski - International Journal of Molecular …, 2021 - mdpi.com
SARS-CoV-2 impairs the renin-angiotensin-aledosterone system via binding ACE2 enzyme.
ACE2 plays a key role in the biosynthesis of angiotensin (1-7), catalyzing the conversion of …

Effect of ramipril on kidney, lung and heart ACE2 in a diabetic mice model

A Vergara, C Jacobs-Cachá… - Molecular and Cellular …, 2021 - Elsevier
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible
for the current coronavirus disease 2019 (COVID-19). The main organ affected in this …

Renin-angiotensin-aldosterone system in new coronavirus infection 2019

NS Zagidullin, DF Gareeva… - " Arterial'naya …, 2020 - htn.almazovcentre.ru
The new coronavirus infection (COVID-19) is a serious threat to humanity. Although its
pathogenesis has not been fully studied, angiotensin-converting enzyme 2 (ACE 2) has …

Effects of SARS-CoV-2 on cardiovascular system: the dual role of angiotensin-converting enzyme 2 (ACE2) as the virus receptor and homeostasis regulator-review

A Aleksova, G Gagno, G Sinagra, AP Beltrami… - International journal of …, 2021 - mdpi.com
Angiotensin-converting enzyme 2 (ACE2) is the entry receptor for severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2), the cause of Coronavirus Disease-2019 (COVID …

Comparison of captopril and enalapril to study the role of the sulfhydryl-group in improvement of endothelial dysfunction with ACE inhibitors in high dieted methionine …

YH Liu, LY Liu, JX Wu, SX Chen… - Journal of cardiovascular …, 2006 - journals.lww.com
To examine the role of sulfhydryl (-SH) group in improvement of endothelial dysfunction with
angiotensin-converting enzyme (ACE) inhibitors in experimental high dose of methionine …