Angiotensin-converting-enzyme 2 and renin-angiotensin system inhibitors in COVID-19: an update

AK Shukla, M Banerjee - High Blood Pressure & Cardiovascular …, 2021 - Springer
Ever since its outbreak, Corona Virus Disease 2019 (COVID-19) caused by SARS-CoV-2
has affected more than 26 million individuals in more than 200 countries. Although the …

Angiotensin-converting enzyme 2 roles in the pathogenesis of COVID-19

A Kenarkoohi, M Maleki, T Safari… - Current hypertension …, 2021 - ingentaconnect.com
The new pandemic Coronavirus Disease 2019 (COVID-19) causes a wide range of clinical
consequences, from asymptomatic infection to acute respiratory failure, and it is very …

Characterization of ACE Inhibitors and AT1R Antagonists with Regard to Their Effect on ACE2 Expression and Infection with SARS-CoV-2 Using a Caco-2 Cell Model

P Reus, AK Schneider, T Ulshöfer, M Henke, D Bojkova… - Life, 2021 - mdpi.com
Blood-pressure-lowering drugs are proposed to foster SARS-CoV-2 infection by
pharmacological upregulation of angiotensin-converting enzyme 2 (ACE2), the binding …

Ace-inhibition with quinapril modulates the nitric oxide pathway in normotensive rats

T Bachetti, L Comini, E Pasini, A Cargnoni… - Journal of molecular and …, 2001 - Elsevier
Angiotensin-converting enzyme (ACE) inhibitors exert some cardiovascular benefits by
improving endothelial function. We evaluated the effects of chronic treatment with quinapril …

Might renin–angiotensin system blockers play a role in the COVID-19 pandemic?

A Battistoni, M Volpe - European Heart Journal-Cardiovascular …, 2020 - academic.oup.com
Since December 2019, a new coronavirus, named SARS-CoV-2, has spread globally,
affecting> 200 000 people worldwide with the so-called COVID-19 disease. The scientific …

[引用][C] Angiotensin-converting enzyme inhibitors may increase risk of severe COVID-19 infection

MAH ALZobaidy, AH AlbuRghaif, HA Alhasany… - Annals of the Romanian …, 2021

Combination therapy with pemafibrate (K-877) and pitavastatin improves vascular endothelial dysfunction in dahl/salt-sensitive rats fed a high-salt and high-fat diet

M Yoshida, K Nakamura, T Miyoshi, M Yoshida… - Cardiovascular …, 2020 - Springer
Background Statins suppress the progression of atherosclerosis by reducing low-density
lipoprotein (LDL) cholesterol levels. Pemafibrate (K-877), a novel selective peroxisome …

The impact of angiotensin-converting enzyme-2/angiotensin 1-7 Axis in establishing severe COVID-19 consequences

MA Maranduca, DM Tanase, CT Cozma, N Dima… - Pharmaceutics, 2022 - mdpi.com
The COVID-19 pandemic has put a tremendous stress on the medical community over the
last two years. Managing the infection proved a lot more difficult after several research …

Effects of combined olmesartan and pravastatin on glucose intolerance and cardiovascular remodeling in a metabolic-syndrome model

M Mizukawa, K Ohmori, A Obayashi, Y Ishihara… - Hypertension …, 2009 - nature.com
Hypertension and dyslipidemia frequently coexist in patients with progressive insulin
resistance and thus constitute metabolic syndrome. We sought to determine the merits of …

Enalapril and quinapril improve endothelial vasodilator function and aortic eNOS gene expression in L-NAME-treated rats

VDG Colonna, G Rossoni, AE Rigamonti… - European journal of …, 2002 - Elsevier
Endothelial dysfunction ensuing inhibition of nitric oxide synthase (NOS) was investigated in
male Sprague–Dawley rats given Nω-nitro-l-arginine methyl ester (l-NAME) in drinking …