Enhanced renin–angiotensin activity causes hypertension and cardiac hypertrophy. The
angiotensin (Ang)-converting enzyme (ACE) 2/Ang (1–7)/Mas axis pathway functions …

There is current debate concerning the use of angiotensin-converting enzyme (ACE)
inhibitors or angiotensin II type 1 receptor blockers (ARBs), for hypertension management …

Background Coronavirus disease 2019 (COVID-19), caused by a novel coronavirus
(designated as SARS-CoV-2) has become a pandemic worldwide. Based on the current …

Pharmacological blockade of the renin–angiotensin–aldosterone system (RAAS) with
angiotensin-converting enzyme (ACE)-inhibitors and angiotensin receptor blockers (ARBs) …

Abstract As of August 16, 2021, there have been 207,173,086 confirmed cases and
4,361,996 deaths due to the coronavirus disease (COVID-19), and the pandemic remains a …

BACKGROUND Coronavirus disease 2019 (COVID‐19) is the cause of a pandemic disease,
with severe acute respiratory syndrome by binding target epithelial lung cells through …

To study the mechanisms of vascular dysfunction in diabetes mellitus, we examined the
responses of the aorta to adrenomedullin (AM) and ANG II in obese Zucker (OZ), lean …

Background Activation of phosphatidylinositol 3-kinase (PI3K)-Akt signaling by statins
increases the activity of endothelial nitric oxide synthase (eNOS). We investigate whether …

Abstract Corona virus disease (COVID-19), caused by SARS-CoV-2, is rapidly spreading all
around the world and is posing a threat to mankind. Since SARS-CoV-2 is a novel virus, little …

13 Mar 2020 Based on initial reports from China, and subsequent evidence that arterial
hypertension may be associated with increased risk of mortality in hospitalized COVID-19 …