Objective To determine the protein expression of Calpain I, mRNA and protein expressions
and activity of calcineurin, and the alternative splicing of Ca/calmodulin-dependent protein …

Objective To investigate the effects of valsartan on myocardial expression and activity of
calcium/calmodulin-dependent protein kinase-II (CaMK II) in a rabbit model of heart failure …

OBJECTIVE: To investigate the regulation of calcium sensitive signal substance calpain in
signal transduction of myocardial remodeling in patients with congestive heart failure …

Objective To evaluate the effects of losartan, an angiotensin receptor blocker, ramipril, an
angiotensin converting enzyme inhibitor, and their combination on left ventricular …

Objective: To test whether olmesartan ameliorates cardiac diastolic dysfunction in
spontaneously hypertensive rats (SHRs) through calcineurin pathway. Methods: Twenty-four …

Introduction. Recently, calcineurin has been shown to induce cardiac hypertrophy. Mitogen-
activated protein kinases (MAPK), including the extracellular-signal regulated kinases …

OBJECTIVE: To investigate whether valsartan exerts its effect on cardiac function in mice
with diabetes mellitus (DM) via Ca2+/calmodulin-dependent protein kinase II (CaMKII) …

Accumulating evidence suggests an important role of the calcineurin signaling pathway in
mediating the development of cardiac hypertrophy. It has also been reported that …

The objective was to investigate the effects of valsartan on the electrophysiological
characteristics of left ventricular hypertrophic myocardium in spontaneously hypertensive …

The present study investigated the role and regulation of calcineurin-dependent signal
pathway in cardiac hypertrophy of rats from the three levels of animal model, culturing cells …