The mucosal immune system and IgA nephropathy
L Gesualdo, V Di Leo, R Coppo - Seminars in immunopathology, 2021 - Springer
The precise pathogenesis of immunoglobulin A nephropathy (IgAN) is still not clearly
established but emerging evidence confirms a pivotal role for mucosal immunity. This review …
established but emerging evidence confirms a pivotal role for mucosal immunity. This review …
The intestine–renal connection in IgA nephropathy
R Coppo - Nephrology Dialysis Transplantation, 2015 - academic.oup.com
It is commonly stated that mucosal immunity plays a role in the pathogenesis of IgA
nephropathy (IgAN); however, the search for specific eliciting factors has been largely …
nephropathy (IgAN); however, the search for specific eliciting factors has been largely …
Immunological drivers of IgA nephropathy: Exploring the mucosa–kidney link
H Selvaskandan, J Barratt… - International Journal of …, 2022 - Wiley Online Library
IgA nephropathy (IgAN) is the most common pattern of primary glomerular disease reported
worldwide. Up to 40% of those with IgAN progress to end‐stage kidney disease within 20 …
worldwide. Up to 40% of those with IgAN progress to end‐stage kidney disease within 20 …
The role of immune modulation in pathogenesis of IgA nephropathy
S Chang, XK Li - Frontiers in Medicine, 2020 - frontiersin.org
IgA nephropathy (IgAN) is the most prevalent primary glomerulonephritis worldwide, with
diverse clinical manifestations characterized by recurrent gross hematuria or microscopic …
diverse clinical manifestations characterized by recurrent gross hematuria or microscopic …
[PDF][PDF] Innate immunity and IgA nephropathy
The hallmark of IgA nephropathy (IgAN) is macroscopic hematuria coinciding with, or
immediately following, a mucosal infection, usually of the upper respiratory airways. The role …
immediately following, a mucosal infection, usually of the upper respiratory airways. The role …
IgA nephropathy: current understanding and perspectives on pathogenesis and targeted treatment
Y Du, T Cheng, C Liu, T Zhu, C Guo, S Li, X Rao, J Li - Diagnostics, 2023 - mdpi.com
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide, with varied clinical and histopathological features between individuals …
worldwide, with varied clinical and histopathological features between individuals …
The mucosa–kidney axis in IgA nephropathy
J Floege, J Feehally - Nature Reviews Nephrology, 2016 - nature.com
Abstract Links between IgA nephropathy (IgAN) and the mucosa have been recognized
since the 1970s. In particular, the observation of visible haematuria induced by respiratory …
since the 1970s. In particular, the observation of visible haematuria induced by respiratory …
[HTML][HTML] An update on the pathogenesis and treatment of IgA nephropathy
JK Boyd, CK Cheung, K Molyneux, J Feehally… - Kidney international, 2012 - Elsevier
Over the past two decades significant progress has been made in unravelling the complex
pathogenesis of immunoglobulin A nephropathy (IgAN). Excess amounts of poorly …
pathogenesis of immunoglobulin A nephropathy (IgAN). Excess amounts of poorly …
The gut–kidney axis in IgA nephropathy: role of microbiota and diet on genetic predisposition
R Coppo - Pediatric nephrology, 2018 - Springer
Recent data suggest that gut-associated lymphoid tissue (GALT) plays a major role in the
development of immunoglobulin A (IgA) nephropathy (IgAN). A genome-wide association …
development of immunoglobulin A (IgA) nephropathy (IgAN). A genome-wide association …
[HTML][HTML] Perspectives on how mucosal immune responses, infections and gut microbiome shape IgA nephropathy and future therapies
Infections have been considered to play a critical role in the pathogenesis of IgA
nephropathy (IgAN) because synpharyngitic hematuria is a common feature in IgAN …
nephropathy (IgAN) because synpharyngitic hematuria is a common feature in IgAN …