Inhaled diesel exhaust particles result in microbiome-related systemic inflammation and altered cardiovascular disease biomarkers in C57Bl/6 male mice
DT Phillippi, S Daniel, V Pusadkar… - Particle and Fibre …, 2022 - Springer
Background The gut microbiota plays a vital role in host homeostasis and is associated with
inflammation and cardiovascular disease (CVD) risk. Exposure to particulate matter (PM) is …
inflammation and cardiovascular disease (CVD) risk. Exposure to particulate matter (PM) is …
Diesel exhaust particles alter the profile and function of the gut microbiota upon subchronic oral administration in mice
S Van Den Brûle, M Rappe, J Ambroise… - Particle and fibre …, 2021 - Springer
Background Ambient air pollution by particulate matters, including diesel exhaust particles
(DEP), is a major cause of cardiovascular and metabolic mortality worldwide. The …
(DEP), is a major cause of cardiovascular and metabolic mortality worldwide. The …
Probiotics function as immunomodulators in the Intestine in C57Bl/6 male mice exposed to inhaled diesel exhaust particles on a high-fat diet
DT Phillippi, S Daniel, KN Nguyen, BA Penaredondo… - Cells, 2022 - mdpi.com
Epidemiological studies reveal a correlation between air pollution exposure and
gastrointestinal (GI) diseases, yet few studies have investigated the role of inhaled …
gastrointestinal (GI) diseases, yet few studies have investigated the role of inhaled …
[HTML][HTML] Intratracheally instillated diesel PM2. 5 significantly altered the structure and composition of indigenous murine gut microbiota
Y Liu, T Wang, B Si, H Du, Y Liu, A Waqas… - Ecotoxicology and …, 2021 - Elsevier
A diverse and large community of gut microbiota reside in the intestinal tract of various
organisms and play important roles in metabolism and immune homeostasis of its host. The …
organisms and play important roles in metabolism and immune homeostasis of its host. The …
Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and …
S Daniel, D Phillippi, LJ Schneider, KN Nguyen… - Particle and Fibre …, 2021 - Springer
Background Exposure to traffic-generated emissions is associated with the development
and exacerbation of inflammatory lung disorders such as chronic obstructive pulmonary …
and exacerbation of inflammatory lung disorders such as chronic obstructive pulmonary …
Diesel exhaust particle inhalation in conjunction with high-fat diet consumption alters the expression of pulmonary SARS-COV-2 infection pathways, which is mitigated …
K Nguyen-Alley, S Daniel, DT Phillippi… - Particle and Fibre …, 2024 - Springer
Background Both exposure to air pollutants and obesity are associated with increased
incidence and severity of COVID-19 infection; however, the mechanistic pathways involved …
incidence and severity of COVID-19 infection; however, the mechanistic pathways involved …
Differential roles of water-insoluble and water-soluble fractions of diesel exhaust particles in the development of adverse health effects due to chronic instillation of …
Y Xu, Z Li, Y Liu, B Pan, R Peng, W Shao… - Chemical Research …, 2021 - ACS Publications
Ambient fine particulate matter (PM2. 5) has a marked temporospatial variation in chemical
composition, but how the composition of PM2. 5 influences its toxicity remains elusive. To …
composition, but how the composition of PM2. 5 influences its toxicity remains elusive. To …
Metabolic outcomes and changes in innate immunity induced by diesel exhaust particles airway exposure and high-fat high-sucrose diet
Y Hasegawa, T Okamura, H Nakajima, N Kitagawa… - Life Sciences, 2023 - Elsevier
Aims Epidemiological studies have shown that exposure to diesel exhaust particles (DEP) is
associated with metabolic diseases. We used mice with nonalcoholic fatty liver disease …
associated with metabolic diseases. We used mice with nonalcoholic fatty liver disease …
Probiotics ameliorate colon epithelial injury induced by ambient ultrafine particles exposure
X Li, H Sun, B Li, X Zhang, J Cui, J Yun… - Advanced …, 2019 - Wiley Online Library
Diesel exhaust particles (DEPs) are common airborne ultrafine particles (UFPs); however,
few studies have examined their effects on the gastrointestinal tract. To investigate the …
few studies have examined their effects on the gastrointestinal tract. To investigate the …
Diesel exhaust particles dysregulate multiple immunological pathways in murine macrophages: Lessons from microarray and scRNA-seq technologies
M Bhetraratana, LD Orozco, J Hong, G Diamante… - Archives of biochemistry …, 2019 - Elsevier
Exposure to ambient particulate matter has been shown to promote a variety of disorders,
including cardiovascular diseases predominantly of ischemic etiology. However, the …
including cardiovascular diseases predominantly of ischemic etiology. However, the …