Context Human obesity is associated with increased circulating TNF-α, a proinflammatory
cytokine that induces hepatocyte cell death. Objective The potential beneficial effects of …

Aims/hypothesis Proinflammatory and proapoptotic cytokines such as TNF-α are
upregulated in human obesity. We evaluated the association between ghrelin isoforms …

We aim to investigate the preventive and therapeutic effects of ghrelin on a rat NAFLD model
and possible underlying mechanism. Sprague–Dawley rats were fed with high-fat diet for 8 …

Background/objectives Bariatric surgery improves nonalcoholic fatty liver disease (NAFLD)
and nonalcoholic steatohepatitis (NASH), but the underlying mechanisms remain elusive …

Bariatric surgery improves non-alcoholic fatty liver disease (NAFLD). Our aim was to
investigate the potential role of ghrelin isoforms in the resolution of hepatic steatosis after …

Background/Aims: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic
liver disease worldwide. Autophagy is associated with NAFLD. Ghrelin is a gut hormone with …

Background Growing evidence suggests the key role of ghrelin in the onset and progression
of nonalcoholic fatty liver disease (NAFLD). The potential participation of ghrelin and the …

Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are two
of the most common liver diseases associated with obesity, type 2 diabetes and metabolic …

Ghrelin is a stomach-derived growth hormone secretagogue that promotes various
physiological effects, including energy metabolism and amelioration of inflammation. The …

Oxidative stress is a major mechanism underlying the pathogenesis of cardiovascular
disease. Herein we investigate the protective effects of ghrelin in H2O2-induced apoptosis of …