[PDF][PDF] Neurotransmitters in nociceptive modulatory circuits
The mammalian central nervous system possesses well-defined networks that modulate
nociceptive transmission. The most extensively studied are the networks that underlie …
nociceptive transmission. The most extensively studied are the networks that underlie …
Descending facilitatory pathways from the RVM initiate and maintain bilateral hyperalgesia after muscle insult
The rostral ventromedial medulla (RVM) is involved in facilitation of spinal nociceptive
processing and generation of hyperalgesia in inflammatory and neuropathic pain models …
processing and generation of hyperalgesia in inflammatory and neuropathic pain models …
An intensified descending pain-facilitating pathway
ZZ Pan - Drug Discovery Today: Disease Models, 2004 - Elsevier
Various animal models have been used to study mechanisms for chronic pain including
neuropathic pain, inflammatory pain, visceral pain, illness-induced pain, chronic opioid …
neuropathic pain, inflammatory pain, visceral pain, illness-induced pain, chronic opioid …
[HTML][HTML] Brainstem facilitations and descending serotonergic controls contribute to visceral nociception but not pregabalin analgesia in rats
S Sikandar, K Bannister, AH Dickenson - Neuroscience letters, 2012 - Elsevier
Pro-nociceptive ON-cells in the rostral ventromedial medulla (RVM) facilitate nociceptive
processing and contribute to descending serotonergic controls. We use RVM injections of …
processing and contribute to descending serotonergic controls. We use RVM injections of …
How do opioids control pain circuits in the brainstem during opioid-induced disorders and in chronic pain? Implications for the treatment of chronic pain
AR Costa, I Tavares, I Martins - Pain, 2022 - journals.lww.com
Brainstem areas involved in descending pain modulation are crucial for the analgesic
actions of opioids. However, the role of opioids in these areas during tolerance, opioid …
actions of opioids. However, the role of opioids in these areas during tolerance, opioid …
[HTML][HTML] Cellular and circuit diversity determines the impact of endogenous opioids in the descending pain modulatory pathway
KB McPherson, SL Ingram - Frontiers in Systems Neuroscience, 2022 - frontiersin.org
The descending pain modulatory pathway exerts important bidirectional control of
nociceptive inputs to dampen and/or facilitate the perception of pain. The ventrolateral …
nociceptive inputs to dampen and/or facilitate the perception of pain. The ventrolateral …
Divergent functions of the left and right central amygdala in visceral nociception
KE Sadler, NA McQuaid, AC Cox, MN Behun… - Pain, 2017 - journals.lww.com
The left and right central amygdalae (CeA) are limbic regions involved in somatic and
visceral pain processing. These 2 nuclei are asymmetrically involved in somatic pain …
visceral pain processing. These 2 nuclei are asymmetrically involved in somatic pain …
Inhibition of itch by neurokinin 1 receptor (Tacr1)-expressing ON cells in the rostral ventromedial medulla
The rostral ventromedial medulla (RVM) is important in descending modulation of spinal
nociceptive transmission, but it is unclear if these descending pathways also modulate …
nociceptive transmission, but it is unclear if these descending pathways also modulate …
Brain mechanisms supporting discrimination of sensory features of pain: a new model
Y Oshiro, AS Quevedo, JG McHaffie… - Journal of …, 2009 - Soc Neuroscience
Pain can be very intense or only mild, and can be well localized or diffuse. To date, little is
known as to how such distinct sensory aspects of noxious stimuli are processed by the …
known as to how such distinct sensory aspects of noxious stimuli are processed by the …