[HTML][HTML] The state-of-the-art of phase II/III clinical trials for targeted pancreatic cancer therapies

A Garcia-Sampedro, G Gaggia, A Ney… - Journal of Clinical …, 2021 - mdpi.com
Pancreatic cancer is a devastating disease with very poor prognosis. Currently, surgery
followed by adjuvant chemotherapy represents the only curative option which, unfortunately …

Pancreatic cancer: current and future treatment strategies

K Pliarchopoulou, D Pectasides - Cancer treatment reviews, 2009 - Elsevier
Pancreatic cancer is a disease with a high mortality rate and short survival, as a result of the
high incidence of metastatic disease at diagnosis, the fulminant clinical course and the lack …

[HTML][HTML] Targeted therapies for pancreatic cancer: overview of current treatments and new opportunities for personalized oncology

C Leroux, G Konstantinidou - Cancers, 2021 - mdpi.com
Simple Summary The lack of early diagnosis and the absence of suitable biomarkers
coupled with resistance to available therapeutic options render pancreatic cancer one of the …

[HTML][HTML] Current and emerging therapeutic strategies in pancreatic cancer: Challenges and opportunities

M Manrai, T Tilak, S Dawra, S Srivastava… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Pancreatic carcinoma (PC) is one of the leading causes of cancer-related deaths worldwide.
Despite early detection and advances in therapeutics, the prognosis remains dismal. The …

Defining new paradigms for the treatment of pancreatic cancer

K Almhanna, PA Philip - Current treatment options in oncology, 2011 - Springer
Opinion statement Pancreatic cancer (PC) is the fourth leading cause of cancer death in the
United States. Despite significant improvement in understanding disease biology, the 5-year …

[HTML][HTML] Current limitations and novel perspectives in pancreatic cancer treatment

S Robatel, M Schenk - Cancers, 2022 - mdpi.com
Simple Summary This review article presents a synopsis of the key clinical developments,
their limitations, and future perspectives in the treatment of pancreatic cancer. In the first part …

Pancreatic cancer: optimizing treatment options, new, and emerging targeted therapies

EG Chiorean, AL Coveler - Drug design, development and therapy, 2015 - Taylor & Francis
Pancreatic cancer is the fourth leading cause of cancer death in the US and is expected to
become the second leading cause of cancer-related deaths in the next decade. Despite 5 …

Therapeutic developments in pancreatic cancer: current and future perspectives

JP Neoptolemos, J Kleeff, P Michl, E Costello… - Nature reviews …, 2018 - nature.com
The overall 5-year survival for pancreatic cancer has changed little over the past few
decades, and pancreatic cancer is predicted to be the second leading cause of cancer …

Molecular targeted approaches for treatment of pancreatic cancer

ZQ Huang, AK Saluja, V Dudeja… - Current …, 2011 - ingentaconnect.com
Human pancreatic cancer remains a highly malignant disease with almost similar incidence
and mortality despite extensive research. Many targeted therapies are under development …

An update on treatment options for pancreatic adenocarcinoma

A Lambert, L Schwarz, I Borbath… - … in medical oncology, 2019 - journals.sagepub.com
Pancreatic cancer is one of the most lethal solid organ tumors. Due to the rising incidence,
late diagnosis, and limited treatment options, it is expected to be the second leading cause …