Nanoconjugates have matured from simple devices to multifunctional, biodegradable, non–
toxic and non–immunogenic constructs, capable of delivering synergistically functioning …

The present study evaluates the efficacy of drug polymer self folding nano-conjugates of
pectin-cisplatin to enhance blood circulating levels of cisplatin. The binding of nano …

Pancreatic cancer (PanCa) is a lethal disease. Conventional chemotherapies for PanCa
offer severe systemic toxicities. Thus, the development of a successful nanomedicine-based …

The fabrication and evaluation of a natural pectin-based drug delivery system are reported
in this study. The drug delivery system displays specific active targeting ability to …

Pectin, a naturally occurring biopolymer has been found to have increasing applications in
the pharmaceutical and biotechnology industry. Sugars with their three-dimensional …

The aim of this study was to investigate the pharmacokinetics and biodistribution in Sprague-
Dawley rats, anti-tumor activity and acute toxicity in different tumor-bearing mice of novel …

By using pectin (PEC) as carrier material and doxorubicin (DOX) as a model drug, the blank
PEC nanoparticles (PEC-NPs) and the DOX-loading PEC nanoparticles (DOX-PEC-NPs) …

Objective: This work has aimed to develop methotrexate-conjugated pectin nanoparticle for
delivering a cytotoxic drug to hepatic cancer cell. Methods: Methotrexate was conjugated to …

In this paper, pectin was cross-linked by a coupling reaction with either thioglycolic acid or
cystamine dihydrochloride to form thiolated pectins. The thiolated pectins were then coupled …

Chitosan has been widely explored as one of the most favorable biomaterials for various
pharmaceutical applications due to its biodegradability and biocompatibility. Here, we report …