Common variation in the gene encoding the neuron-specific RNA splicing factor RNA
Binding Fox-1 Homolog 1 (RBFOX1) has been identified as a risk factor for several …

The RBFOX1 gene (or A2BP1) encodes a splicing factor important for neuronal
development that has been related to autism spectrum disorder and other …

Neurodevelopmental and neuropsychiatric disorders result from complex interactions
between critical genetic factors and as-yet-unknown environmental components. To gain …

Background RBFOX1 (also known as FOX1 or A2BP1) regulates alternative splicing of a
variety of transcripts crucial for neuronal functions. Physiological significance of RBFOX1 …

RBFOX3 mutations are linked to epilepsy and cognitive impairments, but the underlying
pathophysiology of these disorders is poorly understood. Here we report replication of …

Gene abnormalities in RBFOX1, encoding an mRNA-splicing factor, have been shown to
cause autism spectrum disorder and other neurodevelopmental disorders. Since …

Human genetic studies have identified the neuronal RNA binding protein, Rbfox1, as a
candidate gene for autism spectrum disorders. While Rbfox1 functions as a splicing …

Dysfunction of RBFOX3 has been identified in neurodevelopmental disorders such as
autism spectrum disorder, cognitive impairments and epilepsy and a causal relationship with …

Neurodevelopmental disorders are multi-faceted and can lead to intellectual disability,
autism spectrum disorder and language impairment. Mutations in the Forkhead box FOXP1 …

Abstract Objectives. The FoxP2 gene, located on 7q31, encodes a transcription factor. It was
first discovered through investigations of a large multigenerational family (the KE family) with …