Anthraquinone: a promising scaffold for the discovery and development of therapeutic agents in cancer therapy
Cancer, characterized by uncontrolled malignant neoplasm, is a leading cause of death in
both advanced and emerging countries. Although, ample drugs are accessible in the market …
both advanced and emerging countries. Although, ample drugs are accessible in the market …
[HTML][HTML] Journey of anthraquinones as anticancer agents–a systematic review of recent literature
Anthraquinones are privileged chemical scaffolds that have been used for centuries in
various therapeutic applications. The anthraquinone moiety forms the core of various …
various therapeutic applications. The anthraquinone moiety forms the core of various …
Novel anthraquinone compounds as anticancer agents and their potential mechanism
W Tian, C Wang, D Li, H Hou - Future medicinal chemistry, 2020 - Taylor & Francis
Anthraquinones exhibit a unique anticancer activity. Since their discovery, medicinal
chemists have made several structural modifications, resulting in the design and synthesis of …
chemists have made several structural modifications, resulting in the design and synthesis of …
Advances in the discovery of anthraquinone-based anticancer agents
AS Tikhomirov, AA Shtil… - Recent patents on anti …, 2018 - ingentaconnect.com
Background: The anthracene-9, 10-dione (anthraquinone) derivatives represent an
exceptionally valuable class in anticancer drug development. An outstanding antitumor …
exceptionally valuable class in anticancer drug development. An outstanding antitumor …
Alkylating agents, the road less traversed, changing anticancer therapy
D Karati, KR Mahadik, P Trivedi… - Anti-Cancer Agents in …, 2022 - ingentaconnect.com
Cancer is considered one of the gruelling challenges and poses a grave health hazard
across the globe. According to the International Agency for Research on Cancer (IARC) …
across the globe. According to the International Agency for Research on Cancer (IARC) …
A mode of action study of cationic anthraquinone analogs: A new class of highly potent anticancer agents
Previously, we reported the synthesis and structure–activity relationship (SAR) study of a
series of novel 4, 9-dioxo-4, 9-dihydro-1H-naphtho [2, 3-d][1, 2, 3] triazol-3-ium salts, which …
series of novel 4, 9-dioxo-4, 9-dihydro-1H-naphtho [2, 3-d][1, 2, 3] triazol-3-ium salts, which …
[HTML][HTML] The versatile emodin: A natural easily acquired anthraquinone possesses promising anticancer properties against a variety of cancers
Q Zhang, WW Chen, X Sun, D Qian… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Cancers are generally recognized as the leading cause of death and a predominant barrier
to prolonging life expectancy in both developed and developing countries. Emodin is a …
to prolonging life expectancy in both developed and developing countries. Emodin is a …
Recent developments in the synthesis and anti-cancer activity of acridine and xanthine-based molecules
S Majhi - Physical Sciences Reviews, 2023 - degruyter.com
Cancer is the uncontrolled growth and development of abnormal cells which is a major
cause of death in both advanced and emerging countries. Although currently chemotherapy …
cause of death in both advanced and emerging countries. Although currently chemotherapy …
An overview of privileged scaffold: quinolines and isoquinolines in medicinal chemistry as anticancer agents
Y Mao, K Soni, C Sangani, Y Yao - Current Topics in Medicinal …, 2020 - ingentaconnect.com
Cancer is one of the most difficult diseases and causes of death for many decades. Many
pieces of research are continuously going on to get a solution for cancer. Quinoline and …
pieces of research are continuously going on to get a solution for cancer. Quinoline and …
[HTML][HTML] Insights into the computer-aided drug design and discovery based on anthraquinone scaffold for cancer treatment: A protocol for systematic review
There is still unmet medical need in cancer treatment mainly due to drug resistance and
adverse drug events. Therefore, the search for better drugs is essential. Computer-aided …
adverse drug events. Therefore, the search for better drugs is essential. Computer-aided …