Macrophages play a key role in disseminated cryptococcosis, a deadly fungal disease
caused by Cryptococcus neoformans. This opportunistic infection can arise following the …

Cryptococcus neoformans is a facultative intracellular pathogen and the causative agent of
cryptococcosis, a disease that is often fatal to those with compromised immune systems. C …

Cryptococcosis is an opportunistic infection due to the ubiquitous yeast Cryptococcus
neoformans. This yeast interacts closely with innate immune cells, leading to various fates …

Cryptococcus neoformans is a facultative intracellular fungal pathogen. Ten-generation-old
(10GEN) C. neoformans cells are more resistant to phagocytosis and killing by …

Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of death
in immunocompromised individuals. The interactions of this yeast with host phagocytes are …

Metabolically quiescent pathogens can persist in a viable non-replicating state for months or
even years. For certain infectious diseases, such as tuberculosis, cryptococcosis …

Macrophages serve as a first line of defense against infection with the facultative
intracellular pathogen, Cryptococcus neoformans (Cn). However, the ability of these innate …

Background Cryptococcus neoformans causes serious disease in immunocompromised
individuals, leading to over 600,000 deaths per year worldwide. Part of this impact is due to …

ABSTRACT A unique aspect of the interaction of the fungus Cryptococcus neoformans with
macrophages is the phenomenon of nonlytic exocytosis, also referred to as “vomocytosis” or …

Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …