Highlights•Mitochondria are involved in various physiochemical and biochemical
processes.•Owing to their crucial role in cellular metabolism, mitochondria are favored …

Any variation in normal cellular function results in mitochondrial dysregulation that occurs in
several diseases, including cancer. Such processes as oxidative stress, metabolism …

Highlights•Dysregulation of mitochondrial metabolism is a hallmark of cancer development.•
Nanoparticles (NPs) enable the efficient and targeted delivery of mitochondrial agents.•NPs …

Mitochondria are critical subcellular organelles that produce most of the adenosine
triphosphate (ATP) as the energy source for most eukaryotic cells. Moreover, recent findings …

Mitochondrial research is presently one of the fastest growing disciplines in biomedicine.
Since the early 1990s, it has become increasingly evident that mitochondrial dysfunction …

Mitochondrial dysfunction contributes to a large variety of human disorders, ranging from
neurodegenerative and neuromuscular diseases, obesity, and diabetes to ischemia …

Mitochondria play critical roles in the regulation of the proliferation and apoptosis of
cancerous cells. Nanosystems for targeted delivery of cargos to mitochondria for cancer …

Background Known as the main site of ATP production and intrinsic apoptosis regulator,
mitochondria play vital roles in physiological functions and pathological progression …

The early understanding of mitochondria posited that they were 'innocent organelles' solely
devoted to energy production and utilisation. Intriguingly, recent findings have outlined in …

Nanomedicines have been designed and developed to deliver anticancer drugs or exert
anticancer therapy more selectively to tumor sites. Recent investigations have gone beyond …