Allergic diseases, mainly mediated by T helper type 2 (Th2) immunity, have become a
worldwide public health problem. Traditional Chinese medicine (TCM) has long been used …

Basophils are important effector cells, which contribute to protection against helminths and
execute proinflammatory effector function during allergic inflammation. Basophils are also …

Basophils that were long thought to have a redundant role in mast cells in the effector
response to allergens and parasites are now being recognized to have important roles in the …

Basophils and mast cells share some features, including basophilic granules in the
cytoplasm, cell surface expression of the high-affinity IgE receptor and release of chemical …

Basophils, the least common granulocytes, represent only~ 0.5% of peripheral blood
leukocytes. Because of the small number and some similarity with mast cells, the functional …

Basophils and mast cells are important effector cells in helminth‐infected host and IgE‐
mediated allergic inflammation. Although they have the same progenitors, basophils and …

Basophils are relatively rare leukocytes that potentially play a role in both systemic
anaphylaxis and, owing to their ability to migrate from the blood into various other tissues, in …

abstract Basophils have long been neglected in immunological studies because they were
regarded as only minor relatives of mast cells. However, recent advances in analytical tools …

Recent reports demonstrate that basophils act as antigen presenting cells to drive Th2 and
IgE responses against protease and protein allergens and helminth parasites. Through …

Basophils have long been suspected as playing more than a bystander role in initiating and
maintaining allergic disorders, despite their relatively low numbers compared with other …