Background Research suggests that cerebral small vessel disease (CSVD), amyloid, and
pTau contribute to age-related cognitive decline. It remains unknown how these factors …

Background White matter lesions (WMLs) are prevalent in nondemented aging and in
Alzheimer disease (AD). Their relationship with cognition in the earliest stages of AD is …

Context White matter lesions (WML) increase the risk of dementia. The relevance of WML
location is less clear. We sought to determine whether a particular WML profile, based on …

Imaging and neuropsychological correlates of white matter lesions in different subtypes of Mild
Cognitive Impairment: A systematic review - IOS Press You are viewing a javascript disabled …

Despite extensive research over the last decades the clinical significance of white matter
lesions (WMLs) is still a matter of debate. Here, we review current knowledge of the …

Objective. White matter lesions on brain CT or MRI are a frequent finding in patients with
Alzheimer's disease. However, little is known about the prognostic significance of these …

The effect of white matter lesions (WMLs) on the brain of elderly individuals is unclear. Most
debate has focused on the clinical effect of WMLs on cognitive impairment. Large cross …

Objectives Conflicting results have been reported regarding the association between white
matter lesions (WML) and cognitive impairment. We hypothesized that education, a marker …

Background: Evidence suggests that cerebral white matter lesions (WML) play a role in
cognitive decline. Objective: To assess the impact of cerebral WML on cognitive function …

Background: Brain changes involving the white matter (WM), often an indication of
cerebrovascular pathology, are frequently seen in patients with mild cognitive impairment …