Ischemic white matter damage and cognitive impairment

H Yamauchi - Psychogeriatrics, 2003 - Wiley Online Library
White matter damage may play an important role in the pathogenesis of vascular dementia.
White matter abnormalities are easily visualized as white matter high‐intensity lesions …

Cerebral white matter disease is associated with Alzheimer pathology in a prospective cohort

A Moghekar, M Kraut, W Elkins… - Alzheimer's & …, 2012 - Wiley Online Library
Background Although magnetic resonance imaging (MRI)‐detected white matter disease
has been correlated with cognitive decline in the elderly individuals, it is unclear whether …

[HTML][HTML] Total MRI load of cerebral small vessel disease and cognitive ability in older people

J Staals, T Booth, Z Morris, ME Bastin, AJ Gow… - Neurobiology of …, 2015 - Elsevier
Cerebral small vessel disease (SVD) may cause cognitive dysfunction. We tested the
association between the combined presence of magnetic resonance imaging (MRI) features …

White matter predictors of cognitive functioning in older adults

IB Meier, JJ Manly, FA Provenzano… - Journal of the …, 2012 - cambridge.org
Few studies have applied multiple imaging modalities to examine cognitive correlates of
white matter. We examined the utility of T2-weighted magnetic resonance imaging (MRI) …

White matter and its relationship with cognition in subjective cognitive decline

L Ohlhauser, AF Parker, CM Smart, JR Gawryluk… - Alzheimer's & Dementia …, 2019 - Elsevier
Introduction Subjective cognitive decline (SCD) is the earliest stage on the continuum
toward Alzheimer's disease. This study examined (1) differences in white matter integrity …

Confluent white matter in progression to alzheimer dementia

LC Heng, SH Lim, H Foo… - Alzheimer Disease & …, 2021 - journals.lww.com
Background: Alongside Alzheimer disease pathology, cerebral small vessel disease (CSVD)
contributes to the differential progression rates from mild cognitive impairment (MCI) to …

Heterogeneity in mild cognitive impairment: Differences in neuropsychological profile and associated white matter lesion pathology

L Delano-Wood, MW Bondi, J Sacco… - Journal of the …, 2009 - cambridge.org
This study examined whether distinct neuropsychological profiles could be delineated in a
sample with Mild Cognitive Impairment (MCI) and whether white matter lesion (WML) burden …

White matter and hippocampal volume predict the risk of dementia in patients with cerebral small vessel disease: the RUN DMC study

IWM Van Uden, HM Van Der Holst… - Journal of …, 2016 - content.iospress.com
Background: The relationship between cerebral small vessel disease (SVD) and dementia
has been studied without considering white matter (WM) volume, the microstructural integrity …

Structural changes in white matter lesion patients and their correlation with cognitive impairment

J Wang, Y Liang, H Chen, W Wang… - Neuropsychiatric …, 2019 - Taylor & Francis
Background White matter lesions (WMLs) play a role in cognitive decline and dementia.
Little is known about gray matter (GM) changes in WMLs. This study aimed to investigate GM …

Exploring the contribution of myelin content in normal appearing white matter to cognitive outcomes in cerebral small vessel disease

E Dao, R Tam, GYR Hsiung… - Journal of …, 2021 - content.iospress.com
Background: Myelin damage is a salient feature in cerebral small vessel disease (cSVD). Of
note, myelin damage extends into the normal appearing white matter (NAWM). Currently, the …