Overall survival of super-elderly (85 years or older) advanced non-small cell lung cancer patients with active epidermal growth factor receptor mutations receiving first …

K Kashiwabara, S Fujii, S Tsumura… - Journal of Cancer …, 2021 - Springer
Background The survival benefit of first-line epidermal growth factor receptor-tyrosine kinase
inhibitor (EGFR-TKI) therapy in super-elderly patients with advanced non-small cell lung …

First-line gefitinib therapy for elder advanced non-small cell lung cancer patients with epidermal growth factor receptor mutations: Multicenter phase II trial (NEJ 003 …

Y Minegishi, M Maemondo, S Okinaga… - Journal of Clinical …, 2010 - ascopubs.org
7561 Background: First line treatment by gefitinib for NSCLC patients with EGFR mutations
has been validated by us (NEJ 002 Study) and WJTOG3405. In these studies, patients with …

First-line gefitinib treatment in elderly patients (aged ≥75 years) with non-small cell lung cancer harboring EGFR mutations

T Kuwako, H Imai, T Masuda, Y Miura, K Seki… - Cancer chemotherapy …, 2015 - Springer
Purpose The efficacy of gefitinib [an epidermal growth factor receptor (EGFR) tyrosine
kinase inhibitor] in elderly patients with non-small cell lung cancer (NSCLC) and EGFR …

[HTML][HTML] First-line gefitinib in patients aged 75 or older with advanced non–small cell lung cancer harboring epidermal growth factor receptor mutations: NEJ 003 study

M Maemondo, Y Minegishi, A Inoue… - Journal of Thoracic …, 2012 - Elsevier
Introduction: Recent studies have demonstrated that first-line treatment with gefitinib, an
epidermal growth factor receptor (EFGR)–targeted tyrosine kinase inhibitor, is significantly …

Efficacy of gefitinib for elderly patients with advanced non-small cell lung cancer harboring epidermal growth factor receptor gene mutations: a retrospective analysis

H Uruga, K Kishi, T Fujii, Y Beika, T Enomoto… - Internal …, 2010 - jstage.jst.go.jp
Internal Medicine Vol.49 Page 1 103 □ ORIGINAL ARTICLE □ Efficacy of Gefitinib for Elderly
Patients with Advanced Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor …

First-line gefitinib for elderly patients with advanced non-small cell lung cancer (NSCLC) harboring EGFR mutations: A combined analysis of NEJ studies.

S Narumi, A Inoue, N Morikawa, Y Minegishi… - 2012 - ascopubs.org
7563 Background: The first-line treatment with gefitinib has been established as a standard
of care for advanced NSCLC patients with EGFR mutation by previous studies including …

First-line gefitinib for elderly patients harboring EGFR mutations.

K Asami, T Koizumi, S Amejima, A Morikawa… - Journal of Clinical …, 2010 - ascopubs.org
e18094 Background: Potential treatment strategies for elderly patients (pts) with advanced
non-small cell lung cancer (NSCLC) have not been well investigated. Gefitinib has …

Clinical outcomes in elderly patients administered gefitinib as first-line treatment in epidermal growth factor receptor-mutated non-small-cell lung cancer: retrospective …

K Tateishi, T Ichiyama, K Hirai, T Agatsuma, S Koyama… - Medical oncology, 2013 - Springer
The clinical efficacy and outcomes of gefitinib therapy as a first-line treatment for elderly
patients with non-small-cell lung cancer (NSCLC) with epidermal growth factor receptor …

[HTML][HTML] Epidermal growth factor receptor‑tyrosine kinase inhibitors for non‑small‑cell lung cancer patients aged 80 years or older: A retrospective analysis

M Nakao, H Muramatsu, K Sone… - Molecular and …, 2015 - spandidos-publications.com
The efficacy of epidermal growth factor receptor‑tyrosine kinase inhibitors (EGFR‑TKIs) in
elderly patients with non‑small‑cell lung cancer (NSCLC) remains uncertain. This …

Gefitinib as first-line treatment in elderly epidermal growth factor receptor-mutated patients with advanced lung adenocarcinoma: results of a Nagano Lung Cancer …

K Asami, T Koizumi, K Hirai, S Ameshima… - Clinical lung cancer, 2011 - Elsevier
Introduction Feasibility of gefitinib therapy in elderly patients with non–small-cell lung cancer
is uncertain. This phase II study aimed to investigate the efficacy and usefulness of gefitinib …