The effects of electrical stimulation of cervical vagal afferents (VAS) on the background
activity and on the responses of 25 spinothalamic tract (STT) neurons to noxious stimuli …

Both experimental and clinical studies have shown that psychological manipulations, such
as hypnosis, behavioral modification and cognitive-behavioral therapy, can reduce reports …

The present study examined the role of neurons in different pain-related functions of the
anterior cingulate cortex (ACC) and primary sensorimotor cortex (SmI) by assessing their …

Understanding how neuronal circuits control nociceptive processing will advance the search
for novel analgesics. We use functional imaging to demonstrate that lateral hypothalamic …

Descending input from the rostral ventromedial medulla (RVM) provides positive and
negative modulation of spinal nociceptive transmission and has been proposed to be critical …

Noradrenergic locus coeruleus (LC) is involved in pain regulation. We studied whether
response properties of LC neurons or coeruleospinal antinociception are changed 10–14 …

Neurons in layers I and IV–VII of L7 and S1 were studied in unanesthetized spinal cats.
Each cell was characterized in terms of its responses to electrical stimulation of cutaneous A …

Methods are described which provide quantification of learned operant and innate reflex
responses to a thermal stimulus (heat or cold) and provide matched motor controls. The …

In the thalamus, noradrenergic output from the pontine nucleus locus coeruleus (LC) may
actively shape the response properties of various sensory networks en route to the cortex …

Diffuse noxious inhibitory controls (DNIC) are very powerful long-lasting descending
inhibitory controls, which are pivotal in modulating the activity of spinal and trigeminal …