Few clinical studies have investigated the value of phosphate (P)-lowering therapies in early
chronic kidney disease (CKD) patients in whom hyperphosphataemia has not yet clearly …

Convincing epidemiological data have repeatedly shown that increased phosphate levels
as well as generous phosphate intakes are associated with unfavourable outcome both in …

Phosphate levels are strikingly associated with poor outcomes in chronic kidney disease
(CKD) and endstage renal disease (ESRD) patients. Numerous epidemiological studies …

There is an intimate association between mineral and bone disorders in chronic kidney
disease (CKD) and the extensive burden of cardiovascular disease (CVD) in this population …

Hyperphosphataemia is a clinical consequence of the advanced stages of chronic kidney
disease (CKD). Considerable evidence points to a role of hyperphosphataemia in the …

A complex system of endocrine and paracrine signals exists to control phosphate balance.
Dysregulation of these systems in patients with chronic kidney disease has serious clinical …

The increased awareness that disorders of phosphorus metabolism occur early in the
course of chronic kidney disease fuels interest in early intervention strategies. A post hoc …

The pathogenesis and management of chronic kidney disease-mineral bone disorders
(CKD-MBD) has experienced major changes, but the control of serum phosphorus at all …

Background: There is paucity of clinical evidence on target serum phosphorus levels in early
chronic kidney disease (CKD). Present longitudinal study was done to find target …

Data on calcium and phosphate metabolism in the predialysis stages of chronic kidney
disease (CKD) are scarce when compared with the available information on patients on …