J. Neurochem.(2011) 118, 315–316. Abstract Autophagy is an evolutionarily conserved
homeostatic process for the turnover of cellular contents, organelles and misfolded proteins …

The most prevalent pathological features of many neurodegenerative diseases are the
aggregation of misfolded proteins and the loss of certain neuronal populations. Autophagy …

Autophagy is a catabolic pathway by which misfolded proteins or damaged organelles are
engulfed by autophagosomes and then transported to lysosomes for degradation. Recently …

Autophagy is a highly conserved intracellular pathway involved in the elimination of proteins
and organelles by lysosomes. Known originally as an adaptive response to nutrient …

Autophagy is a constitutive lysosomal catabolic pathway that degrades damaged organelles
and protein aggregates. Neuronal survival is highly dependent on autophagy due to its post …

Autophagy is an evolutionally conserved process by which cytoplasmic contents including
protein aggregates and damaged organelles such as mitochondria and lysosomes, are …

The autophagy-lysosomal pathway is a major proteolytic pathway that in mammalian
systems mainly comprises of macroautophagy and chaperone-mediated autophagy. The …

Autophagy is a major degradation pathway where double-membrane vesicles called
autophagosomes deliver cytoplasmic content to the lysosome. Increasing evidence …

Most neurodegenerative diseases that afflict humans are associated with the
intracytoplasmic deposition of aggregate-prone proteins in neurons and with mitochondrial …

Many neurodegenerative diseases are associated with pathological aggregation of proteins
in neurons. Autophagy is a natural self‐cannibalization process that can act as a powerful …