[HTML][HTML] Epstein–Barr virus in multiple sclerosis: theory and emerging immunotherapies

A Bar-Or, MP Pender, R Khanna, L Steinman… - Trends in molecular …, 2020 - cell.com
New treatments for multiple sclerosis (MS) focused on B cells have created an atmosphere
of excitement in the MS community. B cells are now known to play a major role in disease …

[HTML][HTML] Epstein-Barr virus and multiple sclerosis

G Houen, NH Trier, JL Frederiksen - Frontiers in immunology, 2020 - frontiersin.org
Multiple sclerosis (MS) is a neurologic disease affecting myelinated nerves in the central
nervous system (CNS). The disease often debuts as a clinically isolated syndrome, eg, optic …

Epstein–Barr virus and multiple sclerosis: potential opportunities for immunotherapy

MP Pender, SR Burrows - Clinical & translational immunology, 2014 - Wiley Online Library
Multiple sclerosis (MS) is a common chronic inflammatory demyelinating disease of the
central nervous system (CNS) causing progressive disability. Many observations implicate …

Epstein-Barr virus as a driver of multiple sclerosis

LM Sollid - Science Immunology, 2022 - science.org
Accumulating evidence implicates Epstein-Barr virus (EBV) as an etiological factor in
multiple sclerosis (MS). If EBV is a “driver” that causes antiviral immunity with associated …

The role of Epstein-Barr virus in the etiology of multiple sclerosis: a current review

K Ruprecht - Expert review of clinical immunology, 2020 - Taylor & Francis
Introduction: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the
central nervous system. While its exact etiology is unknown, it is generally believed that MS …

[HTML][HTML] Epstein–Barr virus and multiple sclerosis

SS Soldan, PM Lieberman - Nature Reviews Microbiology, 2023 - nature.com
Epstein–Barr virus (EBV) is a ubiquitous human lymphotropic herpesvirus with a well-
established causal role in several cancers. Recent studies have provided compelling …

Epstein–Barr virus as a leading cause of multiple sclerosis: mechanisms and implications

K Bjornevik, C Münz, JI Cohen, A Ascherio - Nature Reviews Neurology, 2023 - nature.com
Epidemiological studies have provided compelling evidence that multiple sclerosis (MS) is a
rare complication of infection with the Epstein–Barr virus (EBV), a herpesvirus that infects …

Defective T‐cell control of Epstein–Barr virus infection in multiple sclerosis

MP Pender, PA Csurhes, JM Burrows… - Clinical & …, 2017 - Wiley Online Library
Mounting evidence indicates that infection with Epstein–Barr virus (EBV) has a major role in
the pathogenesis of multiple sclerosis (MS). Defective elimination of EBV‐infected B cells by …

Epstein–Barr virus and multiple sclerosis. From evidence to therapeutic strategies

S Fernández-Menéndez, M Fernández-Morán… - Journal of the …, 2016 - Elsevier
Multiple sclerosis is caused by a complex interaction between genetic predisposition and
environmental factors. Epstein–Barr virus (EBV) is an environmental risk factor that is …

The essential role of Epstein-Barr virus in the pathogenesis of multiple sclerosis

MP Pender - The Neuroscientist, 2011 - journals.sagepub.com
There is increasing evidence that infection with the Epstein-Barr virus (EBV) plays a role in
the development of multiple sclerosis (MS), a chronic inflammatory demyelinating disease of …