Renal ischemia/reperfusion (I/R) is a common cause of acute kidney injury and remote liver
damage is an ultimate negative outcome. Current treatments for renal I/R typically involve …

Recent evidence has shown that reactive oxygen species (ROS), inflammation and the
activation of JAK/STAT signalling are major pathways in the induction and progression of …

Remote organ damage is the major cause of death in patients with acute kidney injury (AKI)
due to renal ischemia reperfusion (IR). Liver is one of the vital organs which are profoundly …

Renal ischemia/reperfusion (I/R) injury is a major cause of acute kidney injury (AKI) by
increasing oxidative stress, inflammatory responses, and tubular cell death. Oxypurinol, an …

Oxygen metabolites play an important role in the pathogenesis of myoglobinuric acute renal
failure (ARF). Previously, we have reported a down regulation of peroxisome proliferator …

Renal ischemia-reperfusion injury (IRI) is considered as a major cause of acute kidney
injury. In this study, we investigated the role of the NF-κB signaling pathway and …

Background Renal ischemia-reperfusion injury (RIRI) is a critical phenomenon that
compromises renal function and is the most serious health concern related to acute kidney …

Despite the documented renoprotective effect of pentoxifylline (PTX), a non-selective
phosphodiesterase-4 inhibitor, the studies appraised only its anti-inflammatory/-oxidant …

Ischemia/reperfusion injury (IRI) in the kidney is the most common cause of acute renal
dysfunction through different cell damage mechanisms. This study aimed to investigate, on …

Acute kidney injury (AKI) induced by renal ischemia/reperfusion injury (IRI) is a severe
clinical condition. ROS accumulation, antioxidant pathways deficiency, and inflammation are …