Oocyte meiosis is a prolong series of events that are comprised several intermittent
channels in mammals. Oocyte meiosis starts during fetal life and then gets arrested at …

Mammalian oocytes reach prophase of first meiosis around the time of birth, and remain at
this stage for months or years, depending on the species. Only after puberty will the fully …

Resumption of meiosis in mammalian oocytes, defined as oocyte maturation, is stimulated
by luteinizing hormone (LH). Fully grown oocytes can also mature spontaneously, upon their …

The level of cyclic adenosine monophosphate (cAMP) within oocytes has been shown to
play a critical role in maintaining meiotic arrest. High levels of intracellular cAMP prevent …

A central dogma of mammalian reproductive biology is that the size of the primordial follicle
pool represents reproductive capacity in females. The assembly of the primordial follicle …

Meiotic cell cycle in mammalian oocyte is a protracted process that involves several stop
newlineand go channels. It starts during fetal life and gets arrested at diplotene stage of first …

Cyclic nucleotide phosphodiesterases (PDEs) are group of enzymes that hydrolyze cyclic
nucleotides in wide variety of cell types including encircling granulosa cells as well as …

Following early embryonic germ cell migration, oocytes are surrounded by somatic cells and
remain arrested at diplotene stage until luteinizing hormone (LH) surge. Strict regulation of …

The oocyte quality remains as one of the major problems associated with poor in vitro
fertilization (IVF) rate and assisted reproductive technology (ART) failure worldwide. The …

Normal female fertility relies on proper development of the oocyte. This growth culminates
just prior to ovulation, when oocyte maturation occurs. Oocyte maturation refers to a release …