Acute kidney injury (AKI) remains a frequent and serious complication of human sepsis that
contributes significantly to mortality. For better understanding of the development of AKI …

The mortality rate for septic patients with acute renal failure is approximately doubled
compared with patients with sepsis alone. Unfortunately, the treatment for sepsis-induced …

Septic acute kidney injury (S-AKI) is the most common cause of kidney injury in the ICU.
Decreased renal blood flow and inflammation have both been suggested as mechanisms of …

Sepsis is a severe and dysregulated inflammatory response to infection characterized by
end-organ dysfunction distant from the primary site of infection. Development of acute kidney …

Sepsis is a leading cause of acute kidney injury (AKI) and mortality in children.
Understanding the development of pediatric sepsis and its effects on the kidney are critical …

An understanding of the pathologic mechanisms of sepsis-induced AKI emphasizes the
important role of maladaptive responses to the septic insult. Preventive and therapeutic …

Severe sepsis is often accompanied by acute kidney injury (AKI) and albuminuria. Here we
studied whether the AKI and albuminuria associated with lipopolysaccharide (LPS) …

Acute kidney injury (AKI) is a serious condition that affects many ICU patients. The most
common causes of AKI in ICU are severe sepsis and septic shock. The mortality of AKI in …

Acute kidney injury is a frequent and serious complication of sepsis. To better understand
the development of sepsis-induced acute kidney injury, we performed the first time …

The renal microcirculation plays a major role in the delivery of blood and oxygen to the
kidney. In sepsis, alterations in renal microvascular perfusion, in conjunction with increased …