Acute kidney injury (AKI) is a common complication of hospitalized patients, and clinical
outcomes remain poor despite advances in renal replacement therapy. The accepted …

Acute kidney injury (AKI) is a common sequel of sepsis in the intensive care unit. It is being
suggested that sepsis-induced AKI may have a distinct pathophysiology and identity …

Despite identification of several cellular mechanisms being thought to underlie the
development of septic acute kidney injury (AKI), the pathophysiology of the occurrence of …

Acute kidney injury (AKI) and sepsis carry consensus definitions. The simultaneous
presence of both identifies septic AKI. Septic AKI is the most common AKI syndrome in ICU …

Background Hyperdynamic sepsis is often complicated by renal dysfunction, caused in part
by renal vasoconstriction and impaired blood flow. Nitric oxide (NO) is an important mediator …

Sepsis is an important cause of morbidity and mortality. Acute kidney injury often
complicates sepsis, leading to greater complexity, cost of care, and worsening prognosis. In …

Sepsis is the most common cause of acute kidney injury (AKI). There has been a growing
body of evidence demonstrating the association between worsening of kidney function …

Acute renal failure (ARF) is a frequent and serious complication of endotoxemia caused by
lipopolysaccharide (LPS) and contributes significantly to mortality. The present studies were …

Sepsis is a dysregulated immune response to an infection that leads to organ dysfunction.
Knowledge of the pathophysiology of organ failure in sepsis is crucial for optimizing the …

The incidence and mortality of sepsis and the associated development of acute kidney injury
(AKI) remain high, despite intense research into potential treatments. Targeting the …