Spinal dorsal horn neuronal responses to myelinated versus unmyelinated heat nociceptors and their modulation by activation of the periaqueductal grey in the rat

S McMullan, BM Lumb - The Journal of physiology, 2006 - Wiley Online Library
The aim of this study was to further understand the central processing of inputs arising from
unmyelinated and myelinated nociceptors by (i) determining the response characteristics of …

Midbrain control of spinal nociception discriminates between responses evoked by myelinated and unmyelinated heat nociceptors in the rat

S McMullan, BM Lumb - Pain, 2006 - Elsevier
Descending control of spinal nociception is a major determinant of normal and chronic pain.
Myelinated (A-fibre) and unmyelinated (C-fibre) nociceptors convey different qualities of the …

Fos-like immunoreactivity in the superficial medullary dorsal horn induced by noxious and innocuous thermal stimulation of facial skin in the rat

AM Strassman, BP Vos, Y Mineta… - Journal of …, 1993 - journals.physiology.org
1. To examine further the ability of different classes of nociceptive and nonnociceptive
primary afferent neurons to induce c-fos expression in central neurons, fos-like …

Inhibition of spinal neuronal responses to noxious skin heating by stimulation of mesencephalic periaqueductal gray in the cat

E Carstens, T Yokota… - Journal of …, 1979 - journals.physiology.org
1. Discharges of lumbar dorsal horn neurons were evoked by noxious radiant skin heating,
and inhibition of the heat-evoked responses by stimulation of the mesencephalic …

Laminar organization of spinal dorsal horn neurones activated by C‐vs. A‐heat nociceptors and their descending control from the periaqueductal grey in the rat

S Koutsikou, DM Parry, FM MacMillan… - European Journal of …, 2007 - Wiley Online Library
The periaqueductal grey can differentially control A‐vs. C‐nociceptor‐evoked spinal reflexes
and deep spinal dorsal horn neuronal responses. However, little is known about the control …

Quantitative comparison of inhibition in spinal cord of nociceptive information by stimulation in periaqueductal gray or nucleus raphe magnus of the cat

GF Gebhart, J Sandkuhler… - Journal of …, 1983 - journals.physiology.org
The descending inhibition of spinal neuronal responses by focal electrical stimulation in the
periaqueductal gray (PAG) or nucleus raphe magnus (NRM) was quantitatively studied and …

Time course and effective sites for inhibition from midbrain periaqueductal gray of spinal dorsal horn neuronal responses to cutaneous stimuli in the cat

E Carstens, D Klumpp, M Zimmermann - Experimental Brain Research, 1980 - Springer
Inhibition of spinal dorsal horn neuronal responses to noxious (50° C) skin heating by
stimulation of the midbrain periaqueductal gray (PAG) was quantitatively investigated in cats …

Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: behavioral evidence

DC Yeomans, V Pirec, HK Proudfit - Pain, 1996 - Elsevier
Several lines of evidence suggest that different classes of nociceptive afferents mediate the
responses produced by different rates of noxious skin heating. More specifically, low skin …

Quantitative comparison of inhibition of visceral and cutaneous spinal nociceptive transmission from the midbrain and medulla in the rat

TJ Ness, GF Gebhart - Journal of neurophysiology, 1987 - journals.physiology.org
1. The descending inhibition of neuronal responses by focal electrical stimulation or
glutamate microinjections in the periaqueductal gray (PAG) or rostral ventromedial medulla …

Inhibitory effects evoked from both the lateral and ventrolateral periaqueductal grey are selective for the nociceptive responses of rat dorsal horn neurones

AJ Waters, BM Lumb - Brain research, 1997 - Elsevier
In rats anaesthetized with alphaxalone/alphadolone a comparative study was made of the
inhibitory effects on dorsal horn neurones evoked by chemical stimulation at identified …