[HTML][HTML] Evaluation of 4 merozoite antigens as candidate vaccines against Eimeria tenella infection

X Song, X Yang, T Zhang, J Liu, Q Liu - Poultry Science, 2021 - Elsevier
Coccidiosis, caused by parasites of the genus Eimeria, is one of the most widespread and
economically detrimental diseases in the global poultry industry. Because the merozoite …

Identification and characterization of Eimeria tenella EtTrx1 protein

H Li, L Sun, Y Jiang, B Wang, Z Wu, J Sun… - Veterinary …, 2022 - Elsevier
Thioredoxin (Trx) is a widespread protein regulator of redox reactions in all organisms. It
operates together with NADPH and thioredoxin reductase as a general protein disulfide …

Identification and Application of Epitopes in EtMIC1 of Eimeria tenella Recognized by the Monoclonal Antibodies 1-A1 and 1-H2

N Zhao, S Ming, Y Lu, F Wang, H Li, X Zhang… - Infection and …, 2019 - Am Soc Microbiol
Eimeria tenella microneme-1 protein (EtMIC1) has been proposed to be a transmembrane
protein, but this characteristic has not yet been confirmed experimentally. Furthermore …

The Molecular Characterization and Immunity Identification of Microneme 3 of Eimeria acervulina

ZC Zhang, XC Liu, XC Yang, LR Liu… - Journal of Eukaryotic …, 2016 - Wiley Online Library
The gene of Eimeria acervulina microneme protein 3 (Ea MIC 3) was cloned and
characterized. According to the conserved sequence, the 3′‐and 5′‐ends of Ea MIC 3 …

Improving the immunogenicity and protective efficacy of the EtMIC2 protein against Eimeria tenella infection through random mutagenesis

Z Chen, X Wang, N Zhao, L Han, F Wang, H Li, Y Cui… - Vaccine, 2018 - Elsevier
In recent years, directed evolution has emerged as an efficient tool to develop and identify
novel protein variants. Eimeria tenella microneme-2 (EtMIC2) is a promising vaccine …

[HTML][HTML] The microneme adhesive repeat domain of MIC3 protein determined the site specificity of Eimeria acervulina, Eimeria maxima, and Eimeria mitis

Y Zhang, M Lu, Z Zhang, X Huang, J Huang… - Frontiers in …, 2023 - frontiersin.org
Understanding the determinants of host and tissue tropisms among parasites of veterinary
and medical importance has long posed a substantial challenge. Among the seven species …

Preparation and initial application of monoclonal antibodies that recognize Eimeria tenella microneme proteins 1 and 2

Q Liu, Z Chen, W Shi, H Sun, J Zhang, H Li, Y Xiao… - Parasitology …, 2014 - Springer
Abstract Microneme proteins (MICs) of Eimeria species are critical for motility of the parasite,
identification and binding of host cell-surface proteins, invasion of host cells, and …

[HTML][HTML] Molecular Characterization and Immune Protection of a New Conserved Hypothetical Protein of Eimeria tenella

Q Zhai, B Huang, H Dong, Q Zhao, S Zhu, S Liang, S Li… - PloS one, 2016 - journals.plos.org
The genome sequences of Eimeria tenella have been sequenced, but> 70% of these genes
are currently categorized as having an unknown function or annotated as conserved …

A potential vaccine candidate towards chicken coccidiosis mediated by recombinant Lactobacillus plantarum with surface displayed EtMIC2 protein

HB Huang, YL Jiang, FY Zhou, CW Shi, WT Yang… - Experimental …, 2020 - Elsevier
Eimeria tenella (E. tenella) has caused severe economic loss in chicken production,
especially after the forbidden use of antibiotics in feed. Considering the drug resistant …

Molecular characterization of surface antigen 10 of Eimeria tenella

G Liu, S Zhu, Q Zhao, H Dong, B Huang, H Zhao… - Parasitology …, 2019 - Springer
Chicken coccidiosis is caused by the apicomplexan parasite Eimeria spp. At present, drug
resistance of Eimeria is common because of the indiscriminate use of anticoccidial drugs …