Biodegradable nanoparticles have been well studied as biocompatible delivery systems.
Nanoparticles of less than 200 nm in size can facilitate the passive targeting of drugs to …

One major challenge of current surface modification of nanoparticles is the demand for
chemical reactive polymeric layers, such modification is always complicated, inefficient, and …

A multifunctional theranostic nanoplatform integrated with environmental responses has
been developed rapidly over the past few years as a novel treatment strategy for several …

To improve the performance of nanostructured calcium carbonate in gene delivery, a
hydrophilic polysaccharide, alginate, was added to calcium carbonate co-precipitation …

pH sensitive nanoparticles of carbonate apatite (CA) have been proven to be effective
delivery vehicles for DNA, siRNAs and proteins. More recently, conventional anti-cancer …

Doxorubicin (Dox) is a hydrophilic drug extensively used for treatment of breast, lung, and
ovarian cancer, among others; it is highly toxic and can cause serious side effects on …

Both excess dosages of drug and unwanted drug carrier can lead to severe side effects as
well as the failure of tumor therapy. Here, an Fe3+–gallic acid based drug delivery system is …

In order to increase the therapeutic effect of doxorubicin (DOX) on bone metastases, a
multifunctional micelle was developed by combining pH-sensitive characteristics with bone …

Osteosarcoma is the most common primary malignant bone tumor with the pathological
essence of osteolysis, which seriously reduces the quality of life. To improve the treatment of …

Breast cancer has become the second leading cause of cancer-related mortality in female
wherein more than 90% of breast cancer-related death results from cancer metastasis to …