A comparison of MDMA-assisted psychotherapy to non-assisted psychotherapy in treatment-resistant PTSD: A systematic review and meta-analysis

BJG Illingworth, DJ Lewis… - Journal of …, 2021 - journals.sagepub.com
Rationale: Novel, evidence-based treatments are required for treatment-resistant post-
traumatic stress disorder (PTSD). 3, 4-Methylenedioxymethamphetamine (MDMA) has …

[HTML][HTML] MDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial

JM Mitchell, M Ot'alora G, B van der Kolk, S Shannon… - Nature Medicine, 2023 - nature.com
This multi-site, randomized, double-blind, confirmatory phase 3 study evaluated the efficacy
and safety of 3, 4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) versus …

3, 4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for post-traumatic stress disorder in military veterans, firefighters, and police officers: a …

MC Mithoefer, AT Mithoefer, AA Feduccia… - The Lancet …, 2018 - thelancet.com
Background Post-traumatic stress disorder (PTSD) is prevalent in military personnel and first
responders, many of whom do not respond to currently available treatments. This study …

Treating posttraumatic stress disorder with MDMA-assisted psychotherapy: a preliminary meta-analysis and comparison to prolonged exposure therapy

T Amoroso, M Workman - Journal of Psychopharmacology, 2016 - journals.sagepub.com
Since the wars in Iraq and Afghanistan, posttraumatic stress disorder (PTSD) has become a
major area of research and development. The most widely accepted treatment for PTSD is …

Pharmacological-assisted Psychotherapy for Post Traumatic Stress Disorder: a systematic review and meta-analysis

MD Hoskins, R Sinnerton, A Nakamura… - European Journal of …, 2021 - Taylor & Francis
Background: Pharmacological-assisted psychotherapies, using conventional and novel drug
agents, are increasingly being used both in clinical and experimental research settings …

Posttraumatic growth after MDMA‐assisted psychotherapy for posttraumatic stress disorder

I Gorman, AB Belser, L Jerome… - Journal of traumatic …, 2020 - Wiley Online Library
Methylenedioxymethamphetamine (MDMA)–assisted psychotherapy for posttraumatic stress
disorder (PTSD) has been shown to significantly reduce clinical symptomatology, but …

Progress and promise for the MDMA drug development program

AA Feduccia, J Holland, MC Mithoefer - Psychopharmacology, 2018 - Springer
Pharmacotherapy is often used to target symptoms of posttraumatic stress disorder (PTSD),
but does not provide definitive treatment, and side effects of daily medication are often …

Durability of improvement in post-traumatic stress disorder symptoms and absence of harmful effects or drug dependency after 3, 4-methylenedioxymethamphetamine …

MC Mithoefer, MT Wagner… - Journal of …, 2013 - journals.sagepub.com
We report follow-up data evaluating the long-term outcomes for the first completed trial of 3,
4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for chronic, treatment …

[HTML][HTML] A proposed mechanism for the MDMA-mediated extinction of traumatic memories in PTSD patients treated with MDMA-assisted therapy

RJ Sottile, T Vida - Frontiers in Psychiatry, 2022 - frontiersin.org
Post-traumatic stress disorder (PTSD) is a devastating psychiatric disorder afflicting millions
of people around the world. Characterized by severe anxiety, intrusive thoughts, pervasive …

Potential psychiatric uses for MDMA

BB Yazar‐Klosinski… - Clinical pharmacology & …, 2017 - Wiley Online Library
Phase II trials of 3, 4‐methylenedioxymethamphetamine (MDMA)‐assisted psychotherapy
have demonstrated initial safety and efficacy for treatment of posttraumatic stress disorder …