The Biology and Pathogenesis of Chronic Myeloid Leukaemia

N Shanmuganathan, B Chereda, JV Melo - Chronic Myeloid Leukemia, 2021 - Springer
Chronic myeloid leukaemia (CML) is a myeloproliferative disorder of the pluripotent stem
cell. Understanding the molecular biology of CML began with the discovery of the …

The biology and pathogenesis of chronic myeloid leukemia

B Chereda, JV Melo - Chronic myeloid leukemia, 2016 - Springer
Chronic myeloid leukaemia (CML) is a myeloproliferative disorder of the haemopoietic stem
cell. Understanding the molecular biology of CML began with the discovery of the …

Natural course and biology of CML

B Chereda, JV Melo - Annals of hematology, 2015 - Springer
Chronic myeloid leukaemia (CML) is a myeloproliferative disorder arising in the
haemopoietic stem cell (HSC) compartment. This disease is characterised by a reciprocal t …

Chronic Chapter 6 myelogenous leukemia

H Kantarjian, E Jabbour, S O'Brien - Molecular Hematology, 2024 - books.google.com
Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm that arises from a
pluripotent stem cell. The Philadelphia (Ph) chromosome results from a reciprocal …

Chronic myelogenous leukemia

A Quintás-Cardama, J Cortes… - U: Provan D, Gribben …, 2010 - books.google.com
Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm that arises from a
pluripotent stem cell. The Philadelphia (Ph) chromosome, which results from a reciprocal …

Chronic myeloid leukaemia

DA Casolari, JV Melo - Chromosomal Translocations and Genome …, 2015 - Springer
Chronic myeloid leukaemia (CML) was the first leukaemia associated with a unique genetic
abnormality, the Philadelphia chromosome. This results from a reciprocal translocation …

Chronic myelogenous leukemia as a paradigm of early cancer and possible curative strategies

B Clarkson, A Strife, D Wisniewski, CL Lambek, C Liu - Leukemia, 2003 - nature.com
The chronological history of the important discoveries leading to our present understanding
of the essential clinical, biological, biochemical, and molecular features of chronic …

Chronic myelogenous leukemia, a still unsolved problem: pitfalls and new therapeutic possibilities

S Flis, T Chojnacki - Drug design, development and therapy, 2019 - Taylor & Francis
Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of hematopoietic
stem cells. At the molecular level, the disorder results from t (9; 22)(q34; q11) reciprocal …

[PDF][PDF] New insights in the pathogenesis of chronic myeloid leukemia: towards a path to cure

JJWM Schuurhuis - Neth J Med, 2011 - research.vumc.nl
Chronic myeloid leukemia (CML) is a myeloproliferative clonal stem cell disease,
consistently associated with a reciprocal translocation between chromosomes 9 and 22. The …

Chronic myeloid leukemia: mechanisms of blastic transformation

D Perrotti, C Jamieson, J Goldman… - The Journal of clinical …, 2010 - Am Soc Clin Investig
The BCR-ABL1 oncoprotein transforms pluripotent HSCs and initiates chronic myeloid
leukemia (CML). Patients with early phase (also known as chronic phase [CP]) disease …